Volume 25, Number 10—October 2019
Research
Comparison of Serologic Assays for Middle East Respiratory Syndrome Coronavirus
Table 1
Samples used in study of serologic assays for MERS-CoV*
No. | Name | Description | Expected result |
---|---|---|---|
1 |
Korea 5 |
Single plasma from laboratory-confirmed MERS patient |
Positive |
2 |
Tc Bovine NC |
Purified IgG from transchromosomal bovine, negative control |
Negative |
3 |
WHO/B |
Negative control serum, high titer for other CoV |
Negative |
4 |
Tc Bovine SAB 300 |
Purified IgG from transchromosomal bovine, antigen whole virus |
Positive |
5 |
Korea 2 |
Single plasma from laboratory-confirmed MERS patient |
Positive |
6 |
WHO/G |
Negative control serum, high titer for other CoV |
Negative |
7 |
WHO/A |
Negative control serum, high titer for other CoV |
Negative |
8 |
WHO/D |
Negative control serum, high titer for other CoV |
Negative |
9 |
Korea 3 |
Single plasma from laboratory-confirmed MERS patient |
Positive |
10 |
Tc Bovine SAB 301 |
Purified IgG from transchromosomal bovine, antigen spike protein |
Positive |
11 |
Korea 1 |
Single plasma from laboratory-confirmed MERS patient |
Positive |
12 |
Korea 4 |
Single plasma from laboratory-confirmed MERS patient |
Positive |
13 |
WHO/F |
Negative control serum, high titer for other CoV |
Negative |
14 |
Pool C (low) |
Pooled serum samples from laboratory-confirmed MERS patients |
Positive |
15 |
WHO/C |
Negative control serum, high titer for other CoV |
Negative |
16 |
Pool A (high) |
Pooled serum samples from laboratory-confirmed MERS patients |
Positive |
17 |
WHO/E |
Negative control serum, high titer for other CoV |
Negative |
18 | Pool B (medium) | Pooled serum samples from laboratory-confirmed MERS patients | Positive |
*All samples were submitted as liquid in screw-cap tubes. CoV, coronavirus; MERS, Middle East respiratory syndrome; Tc, transchromosomal; WHO, World Health Organization.
1Study participants who contributed data are listed at the end of this article.