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Volume 25, Number 10—October 2019
Research

Prevalence of Tuberculosis in Children After Natural Disasters, Bohol, Philippines

Kristy O. Murray, Nina T. Castillo-Carandang, Anna M. Mandalakas, Andrea T. Cruz, Lauren M. Leining, Salvacion R. GatchalianComments to Author , on behalf of the PEER Health Bohol Pediatric Study Team
Author affiliations: Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas, USA (K.O. Murray, A.M. Mandalakas, A.T. Cruz, L.M. Leining); University of the Philippines, Manila, Philippines (N.T. Castillo-Carandang, S.R. Gatchalian)

Main Article

Table 5

Clinical and diagnostic findings for 16 persons with TB in cluster survey of TB in children in areas affected by 2013 natural disasters, Bohol, Philippines, 2016–2018*

Case no. Natural disaster area Age, y/sex Known exposure to TB History of signs/symptoms Chest radiograph interpretation by radiologist DSSM result† GeneXpert result†
1
LAA
6/M
Yes
Cough >2 weeks, wheezing, weight loss; no improvement after taking antimicrobial drugs
Pneumonia, both paracardiac areas
Neg
Neg
2
LAA
2/M
Yes
Cough >2 weeks, weight loss, malaise; no improvement after taking antimicrobial drugs
Inflammatory process, both inner zones
Neg
Invalid, after 2 extractions
3
LAA
8/M
Yes
Cervical lymphadenopathy
Calcified hilar lymphadenopathy, likely representing a chronic process, such as pulmonary TB
Neg
Neg
4
LAA
14/M
Yes
None; history of prior TB treatment but did not complete therapy
Inflammatory process in left apical area compatible with chronic process, such as pulmonary TB with minimal apical pleural thickening
Neg
Neg
5
LAA
7/F
Yes
Cough >2 weeks
Normal
Neg
Neg
6
LAA
4/M
Yes
Cough >2 weeks, weight loss, anorexia, malaise, chest pain
Normal
Neg
Neg
7
LAA
5/M
Yes
Cervical lymphadenopathy
Inflammatory process in the left retrocardiac area
Neg
Neg
8
HAA
14/F
Yes
None
Normal
Neg
Pos
9
LAA
5/F
Yes
Cough >2 weeks, fever, weight loss
Normal
Neg
Pos
10
LAA
1/F
Yes
Cough >2 weeks, fever, dyspnea, no improvement after taking antimicrobial drugs
Normal
Neg
Neg
11
LAA
12/F
No
Coughing >2 weeks, fever, chest and back pain, weight loss, cervical lymphadenopathy
Normal
Neg
Neg
12
LAA
11/F
Yes
Cervical lymphadenopathy, no rales or wheezing
Normal
Neg
Neg
13
LAA
3/M
Yes
Cervical lymphadenopathy
Normal
Neg
Neg
14
LAA
6/M
Yes
Cervical lymphadenopathy
Normal
Neg
Neg
15
LAA
3/F
Yes
Coughing >2 weeks, weight loss
Bilateral pneumonia
Neg
Neg
16 HAA 10/M Yes Coughing >2 weeks, weight loss, cervical lymphadenopathy Pneumonia, both lower lungs, minimal left pleural effusion vs. pleural thickening; consider Potts disease (extrapulmonary TB) involving T12 and L1 vertebrae with Gibbus deformity Neg Pos

*DSSM, direct sputum smear microscopy; HAA, heavily affected area; LAA, less affected area; neg, negative; pos, positive; TB, tuberculosis.
†Direct smears and GeneXpert (Cepheid, http://www.cepheid.com) performed on sputum for children >5 years of age and gastric aspirates for children <5 years of age.

Main Article

1Additional members of the PEER Health Bohol Pediatric Study Team who contributed data are listed at the end of this article.

Page created: September 17, 2019
Page updated: September 17, 2019
Page reviewed: September 17, 2019
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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