TY - JOUR AU - Silveira, Simone AU - Falkenberg, Shollie AU - Kaplan, Bryan AU - Crossley, Beate AU - Ridpath, Julia AU - Bauermann, Fernando AU - Fossler, Charles AU - Dargatz, David AU - Dassanayake, Rohana AU - Vincent, Amy AU - Canal, Cláudio AU - Neill, John T1 - Serosurvey for Influenza D Virus Exposure in Cattle, United States, 2014–2015 T2 - Emerging Infectious Disease journal PY - 2019 VL - 25 IS - 11 SP - 2074 SN - 1080-6059 AB - Influenza D virus has been detected predominantly in cattle from several countries. In the United States, regional and state seropositive rates for influenza D have previously been reported, but little information exists to evaluate national seroprevalence. We performed a serosurveillance study with 1,992 bovine serum samples collected across the country in 2014 and 2015. We found a high overall seropositive rate of 77.5% nationally; regional rates varied from 47.7% to 84.6%. Samples from the Upper Midwest and Mountain West regions showed the highest seropositive rates. In addition, seropositive samples were found in 41 of the 42 states from which cattle originated, demonstrating that influenza D virus circulated widely in cattle during this period. The distribution of influenza D virus in cattle from the United States highlights the need for greater understanding about pathogenesis, epidemiology, and the implications for animal health. KW - influenza D virus KW - bovine KW - epidemiology KW - bovine respiratory disease KW - hemagglutination inhibition assay KW - influenza KW - viruses KW - United States KW - zoonoses DO - 10.3201/eid2511.190253 UR - https://wwwnc.cdc.gov/eid/article/25/11/19-0253_article ER - End of Reference