TY - JOUR AU - Susilawathi, Ni Made AU - Tarini, Ni Made Adi AU - Fatmawati, Ni Nengah Dwi AU - Mayura, Putu I.B. AU - Suryapraba, Anak Agung Ayu AU - Subrata, Made AU - Sudewi, Anak Agung Raka AU - Mahardika, Gusti Ngurah T1 - Streptococcus suis–Associated Meningitis, Bali, Indonesia, 2014–2017 T2 - Emerging Infectious Disease journal PY - 2019 VL - 25 IS - 12 SP - 2235 SN - 1080-6059 AB - Streptococcus suis is an emerging agent of zoonotic bacterial meningitis in Asia. We describe the epidemiology of S. suis cases and clinical signs and microbiological findings in persons with meningitis in Bali, Indonesia, using patient data and bacterial cultures of cerebrospinal fluid collected during 2014–2017. We conducted microbiological assays using the fully automatic VITEK 2 COMPACT system. We amplified and sequenced gene fragments of glutamate dehydrogenase and recombination/repair protein and conducted PCR serotyping to confirm some serotypes. Of 71 cases, 44 were confirmed as S. suis; 29 isolates were serotype 2. The average patient age was 48.1 years, and 89% of patients were male. Seventy-seven percent of patients with confirmed cases recovered without complications; 11% recovered with septic shock, 7% with deafness, and 2% with deafness and arthritis. The case-fatality rate was 11%. Awareness of S. suis infection risk must be increased in health promotion activities in Bali. KW - Streptococcus suis KW - human KW - meningitis KW - Bali KW - Indonesia KW - bacteria KW - pork KW - swine KW - zoonoses KW - meningitis/encephalitis DO - 10.3201/eid2512.181709 UR - https://wwwnc.cdc.gov/eid/article/25/12/18-1709_article ER - End of Reference