TY - JOUR AU - Bozza, Fernando AU - Moreira-Soto, Andres AU - Rockstroh, Alexandra AU - Fischer, Carlo AU - Nascimento, Alessandra AU - Calheiros, Andrea AU - Drosten, Christian AU - Bozza, PatrĂ­cia AU - Souza, Thiago Moreno AU - Ulbert, Sebastian AU - Drexler, Jan Felix T1 - Differential Shedding and Antibody Kinetics of Zika and Chikungunya Viruses, Brazil T2 - Emerging Infectious Disease journal PY - 2019 VL - 25 IS - 2 SP - 311 SN - 1080-6059 AB - In seroconversion panels obtained from patients from Brazil, diagnostic testing for Zika virus infection was improved by combining multiple antibody isotypes, techniques, and antigens, but sensitivity remained suboptimal. In contrast, chikungunya virus diagnostic testing was unambiguous. Recurrent recent arbovirus infections suggested by serologic data and unspecific symptoms highlight the need for exhaustive virologic testing. KW - Zika virus KW - chikungunya virus KW - RT-PCR KW - serology KW - diagnosis KW - viruses KW - vector-borne infections KW - Brazil KW - arboviruses KW - flaviviruses KW - real time RT-PCR DO - 10.3201/eid2502.180166 UR - https://wwwnc.cdc.gov/eid/article/25/2/18-0166_article ER - End of Reference