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Volume 25, Number 2—February 2019
CME ACTIVITY - Research

Acute and Delayed Deaths after West Nile Virus Infection, Texas, USA, 2002–2012

David C.E. Philpott1, Melissa S. Nolan, Nicole Evert, Bonny Mayes, Dawn Hesalroad, Eric Fonken, and Kristy O. MurrayComments to Author 
Author affiliations: Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas, USA (D.C.E. Philpott, M.S. Nolan, K.O. Murray); Texas Department of State Health Services, Austin, Texas, USA (N. Evert, B. Mayes, D. Hesalroad, E. Fonken)

Main Article

Table 2

Causes of convalescent-phase death in persons given a diagnosis of West Nile fever or WNND, Texas, USA, 2002–2012*

ICD-10 code Cause of death or disorder WNND
Non-WNND
No. deaths observed No. deaths expected SMR (95% CI) No. deaths observed No. deaths expected SMR (95% CI)
Any All cause 210 187 1.13 (0.99–1.29) 58 81.08 0.72 (0.55–0.93)
A00-B99 Infectious 26 5.49 4.74 (3.22–6.94) 3 2.57 1.17 (0.38–3.62)
C00-D48 Neoplasms 33 43.89 0.75 (0.53–1.06) 12 19.06 0.63 (0.36–1.11)
E00-E90 Endocrine 11 8.13 1.35 (0.75–2.44) 3 3.60 0.83 (0.27–2.58)
F00-F99 Mental and behavioral 13 8.96 1.45 (0.84–2.50) 1 3.86 0.26 (0.04–1.84)
G00-G99 Nervous system 11 10.70 1.03 (0.57–1.86) 4 4.51 0.89 (0.33–2.36)
I00-I99 Circulatory system 64 63.44 1.01 (0.79–1.29) 18 26.99 0.67 (0.42–1.06)
J00-J99 Respiratory system 13 19.70 0.66 (0.38–1.14) 7 8.12 0.86 (0.41–1.81)
K00-K93 Digestive system 9 6.82 1.32 (0.69–2.53) 1 3.24 0.31 (0.04–2.19)
N00-N99 Genitourinary system 13 5.40 2.41 (1.40–4.15) 2 2.30 0.87 (0.22–3.47)
N00-N19 Renal disease 11 4.25 2.59 (1.43–4.67) 1 1.81 0.55 (0.08–3.92)
R00-R99 Other 5 2.53 1.97 (0.82–4.74) 2 1.18 1.70 (0.43–6.80)
W00-Y98 External forces 10 6.86 1.46 (0.78–2.71) 3 3.77 0.80 (0.26–2.47)

*Deaths and SMRs were calculated only for cases with information about age available and in which death occurred >90 d after symptom onset. SMR was 1 when there was no increased risk. ICD-10, International Classification of Diseases, 10th Revision; SMR, standardized mortality ratio adjusted for current age, sex, and calendar year; WNND, West Nile neuroinvasive disease.

Main Article

1Current affiliation: Johns Hopkins Children’s Center, Baltimore, Maryland, USA.

Page created: January 17, 2019
Page updated: January 17, 2019
Page reviewed: January 17, 2019
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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