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Volume 25, Number 3—March 2019
Dispatch

Genomic Analysis of Cardiac Surgery–Associated Mycobacterium chimaera Infections, United States

Nabeeh A. HasanComments to Author , L. Elaine Epperson, Adrian Lawsin, Rachael R. Rodger, Kiran M. Perkins, Alison Laufer Halpin, K. Allison Perry, Heather Moulton-Meissner, Daniel J. Diekema, Matthew B. Crist, Joseph F. Perz, Max Salfinger, Charles L. Daley, and Michael Strong
Author affiliations: National Jewish Health, Denver, Colorado, USA (N.A. Hasan, L.E. Epperson, R.R. Rodger, M. Salfinger, C.L Daley, M. Strong); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (A. Lawsin, K.M. Perkins, A.L. Halpin, K.A. Perry, H. Moulton-Meissner, M.B. Crist, J.F. Perz); University of Iowa, Iowa City, Iowa, USA (D.J. Diekema)

Main Article

Figure 1

Neighbor Net splitstree of Mycobacterium chimaera isolates: relationships between M. chimaera isolates (n = 124) mapped against the M. chimaera strain CDC 2015–22–71 heater–cooler unit (HCU) reference genome (18,190 single nucleotide polymorphisms [SNPs] in 3,815,639 core positions). Isolates were grouped with a threshold of <500 SNPs to the nearest cluster. Clustered HCU isolates, including the reference strain CDC 2015-22-71, comprise the HCU1 cluster (n = 112) and HCU2 (n = 3). Unclustered

Figure 1. Neighbor Net splitstree of Mycobacterium chimaera isolates: relationships between M. chimaera isolates (n = 124) mapped against the M. chimaera strain CDC 2015–22–71 heater–cooler unit (HCU) reference genome (18,190 single nucleotide polymorphisms [SNPs] in 3,815,639 core positions). Isolates were grouped with a threshold of <500 SNPs to the nearest cluster. Clustered HCU isolates, including the reference strain CDC 2015-22-71, comprise the HCU1 cluster (n = 112) and HCU2 (n = 3). Unclustered isolates include Australian (AUS) HCU isolates (n = 2), USA non-HCU isolates (n=8), and the type strain FI-01069. Scale bar indicates SNPs.

Main Article

Page created: February 19, 2019
Page updated: February 19, 2019
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