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Volume 25, Number 3—March 2019
Research

Increased Risk for Invasive Group A Streptococcus Disease for Household Contacts of Scarlet Fever Cases, England, 2011–2016

Vicky WattsComments to Author , Sooria Balasegaram, Colin S. Brown, Suzanna Mathew, Rachel Mearkle, Derren Ready, Vanessa Saliba, and Theresa Lamagni
Author affiliations: Public Health England, Liverpool, UK (V. Watts); Public Health England, London, UK (S. Balasegaram, C.S. Brown, D. Reddy, V. Saliba, T. Lamagni); Public Health England, Leeds, UK (S. Mathew); Public Health England, Chilton, UK (R. Mearkle)

Main Article

Table 3

Risk for iGAS among household contacts of 66,191 scarlet fever case-patients <10 years of age compared with background iGAS incidence by age, England, 2011–2016*

Age of contacts, y Estimated no. contacts No. iGAS cases in contacts† Attack rate/100,000 person-years (95% CI) Background iGAS incidence/100,000 person-years Rate ratio (95% CI)
<1 8,853 2 137.5 (16.7–496.8) 6.42 21.4 (5.31–86.1)
1–10 28,660 1 21.2 (0.5–118.3) 2.84 7.5 (1.1–53.1)
11–17 22,209 1 27.4 (0.7–152.7) 0.58 43.9 (6.1–313.7)
18–50 122,801 6 29.7 (10.9–64.7) 1.69 18.4 (8.4–41.1)
51–74 6,733 0 0 (0–333.5) 3.59 0
>75 429 1 1,419.2 (35.9–7.907.3) 10.20 139.2 (19.6–988.5)

iGAS, invasive group A Streptococcus infection.
†During the 60 days after onset of scarlet fever in the household.

Main Article

Page created: February 19, 2019
Page updated: February 19, 2019
Page reviewed: February 19, 2019
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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