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Volume 25, Number 3—March 2019
Research

Window Period Prophylaxis for Children Exposed to Tuberculosis, Houston, Texas, USA, 2007–2017

Andrea T. CruzComments to Author  and Jeffrey R. Starke
Author affiliations: Baylor College of Medicine, Houston, Texas, USA; Children’s Tuberculosis Clinic at Texas Children’s Hospital, Houston

Main Article

Table 1

Characteristics of 752 children exposed to index tuberculosis patients, index patients, and index case Mycobacterium tuberculosis isolates, Houston, Texas, USA, 2007–2017

Characteristic Value*
Demographics
Age, y, median (interquartile range) 2.4 (1.2–3.6)
Sex
F 380 (50.5)
M 372 (49.5)
Race/ethnicity
Hispanic 493 (65.6)
Black 141 (18.8)
Asian 78 (10.4)
White 30 (4.0)
Biracial 10 (1.3)
Residing in home of index patient
Yes 311 (41.4)
No
441 (58.6)
Index patient microbiology
Acid-fast bacilli smear positive 513 (68.2)
Acid-fast bacilli culture positive
680 (90.4)
Index isolate drug susceptibilities, n = 680
Isoniazid and rifampin susceptibility 635 (93.4)
Isoniazid resistance† 32 (4.7)
Isoniazid and rifampin resistance 13 (1.9)
Rifampin monoresistance
1 (0.1)
Index patient sample used for culture
Sputum 637 (84.7)
Bronchoalveolar lavage 93 (12.4)
Lung biopsy 11 (1.5)
Pleural fluid 11 (1.5)

*Values are no. (%), except where specified. Percentages might not sum up to 100% because of rounding.
†Seven isolates were resistant to isoniazid and streptomycin, and 5 were resistant to isoniazid and ethambutol; the remainder of isolates had isoniazid monoresistance.

Main Article

Page created: February 19, 2019
Page updated: February 19, 2019
Page reviewed: February 19, 2019
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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