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Volume 25, Number 5—May 2019

Novel Method for Rapid Detection of Spatiotemporal HIV Clusters Potentially Warranting Intervention

Arthur G. FitzmauriceComments to Author , Laurie Linley, Chenhua Zhang, Meg Watson, Anne Marie France, and Alexandra M. Oster
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (A.G. Fitzmaurice, L. Linley, M. Watson, A.M. France, A.M. Oster); ICF International, Atlanta (C. Zhang)

Main Article


Distribution of spatiotemporal clusters of HIV diagnoses among counties in 50 states and the District of Columbia, 2016

All diagnoses

Diagnoses attributable to injection drug use
Counties with alerts, no. (%)*
Counties without alerts, no. (%)
p value
Counties with alerts, no. (%)*
Counties without alerts, no. (%)
p value
Region (7)
Northeast 21 (15) 196 (7) 0.0002 3 (14) 214 (7) 0.18
Midwest 27 (19) 1,028 (34) 0.0001 6 (29) 1,049 (34) 0.63
South 84 (59) 1,338 (45) 0.0009 8 (38) 1,414 (45) 0.51
11 (8)
437 (15)

4 (19)
444 (14)
Baseline mean annual HIV diagnoses, 2013–2015 
<3 52 (36) 2,128 (71) <10–4 13 (62) 2,176 (69) 0.46
3–9 40 (28) 463 (15) <10–4 8 (38) 495 (16) 0.0056
51 (36)
408 (14)

459 (15)
Total counties 143 (100) 2,999 (100) 21 (100) 3,121 (100)

*An alert occurred when the number of diagnoses in 2016 increased by >2 SD and >2 diagnoses compared with the mean annual baseline over the preceding 3 years (2013–2015).

Main Article

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Main Article

Page created: April 17, 2019
Page updated: April 17, 2019
Page reviewed: April 17, 2019
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