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Volume 25, Number 6—June 2019
CME ACTIVITY - Synopsis

Epidemiologic and Clinical Features of Lassa Fever Outbreak in Nigeria, January 1–May 6, 2018

Elsie A. Ilori1, Yuki Furuse1, Oladipupo B. Ipadeola1, Chioma C. Dan-Nwafor1, Anwar Abubakar, Oboma E. Womi-Eteng, Ephraim Ogbaini-Emovon, Sylvanus Okogbenin, Uche Unigwe, Emeka Ogah, Olufemi Ayodeji, Chukwuyem Abejegah, Ahmed A. Liasu, Emmanuel O. Musa, Solomon F. Woldetsadik, Clement L.P. Lasuba, Wondimagegnehu Alemu, Chikwe IhekweazuComments to Author , and Nigeria Lassa Fever National Response Team
Author affiliations: Nigeria Centre for Disease Control, Abuja, Nigeria (E.A. Ilori, O.B. Ipadeola, C.C. Dan-Nwafor, A. Abubakar, O.E. Womi-Eteng, C. Ihekweazu); Kyoto University, Kyoto, Japan (Y. Furuse); World Health Organization, Abuja (Y. Furuse, E.O. Musa, S.F. Woldetsadik, C.L.P. Lasuba, W. Alemu); US Centers for Disease Control and Prevention, Abuja (O.B. Ipadeola); African Field Epidemiology Network, Abuja (C.C. Dan-Nwafor); Irrua Specialist Teaching Hospital, Irrua, Nigeria (E. Ogbaini-Emovon, S. Okogbenin); Federal Teaching Hospital, Abakaliki, Nigeria (U. Unigwe, E. Ogah); Federal Medical Centre, Owo, Nigeria (O. Ayodeji, C. Abejegah, A.A. Liasu)

Main Article

Table 2

Distribution of age and sex among patients with laboratory-confirmed Lassa fever, Nigeria, January 1–May 6, 2018*

Characteristic No. girls and women (deaths) No. boys and men (deaths) Total no. (deaths) Case-fatality rate, % aOR (95% CI) p value
Age group, y
0–10 19 (3) 26 (2) 45 (5) 11.1 Reference
11–20 24 (4) 42 (10) 66 (14) 21.2 2.1 (0.71–6.4) 0.18
21–30 38 (5) 52 (13) 90 (18) 20.5 2.1 (0.71–6.0) 0.18
31–40 30 (7) 60 (16) 90 (23) 25.6 2.7 (0.95–7.6) 0.063
41–50 23 (5) 39 (15) 62 (20) 32.3 3.8 (1.3–11.0) 0.015
51–60 10 (4) 15 (4) 25 (8) 32.0 3.8 (1.1–13.2) 0.039
>61
 12 (5)
 22 (8)
 34 (13)
 38.2
 4.9 (1.5–15.6)
 0.0074
Total 157 (34) 257 (68) 423 (106)
Case-fatality rate, % 21.8 26.6
aOR (95% CI) Reference 1.3 (0.81–2.1)
p value 0.26

*aORs, 95% CIs, and p values calculated by using the binomial logistic regression model for fatal outcomes. Because information on age and sex was missing for some cases, the number of total cases is not equal to sum of the number of cases in all age groups. aOR, adjusted odds ratio.

Main Article

1These first authors contributed equally to this article.

2Other members of the Nigeria Lassa Fever National Response Team are listed at the end of this article.

Page created: May 19, 2019
Page updated: May 19, 2019
Page reviewed: May 19, 2019
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