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Volume 25, Number 6—June 2019

Sequential Emergence and Wide Spread of Neutralization Escape Middle East Respiratory Syndrome Coronavirus Mutants, South Korea, 2015

Yeon-Sook Kim1, Abdimadiyeva Aigerim1, Uni Park1, Yuri Kim, Ji-Young Rhee, Jae-Phil Choi, Wan Beom Park, Sang Won Park, Yeonjae Kim, Dong-Gyun Lim, Kyung-Soo Inn, Eung-Soo Hwang, Myung-Sik Choi, and Nam-Hyuk Cho2Comments to Author 
Author affiliations: Chungnam National University School of Medicine, Daejeon, South Korea (Y.-S. Kim); Seoul National University College of Medicine, Seoul, South Korea (A. Aigerim, U. Park, Y. Kim, W.B. Park, S.W. Park, E.-S. Hwang, M.-S. Choi, N.-H. Cho); Dankook University College of Medicine, Cheonan, South Korea (J.-Y. Rhee); Seoul Medical Center, Seoul (J.-P. Choi); National Medical Center, Seoul (Y. Kim, D.-G. Lim, H.S. Shin); Kyung Hee University, Seoul (K.-S. Inn); Seoul National University Medical Research Center and Bundang Hospital, Seoul (N.H. Cho)

Main Article


Baseline characteristics of MERS patients and associated MERS coronavirus spike genotypes identified from the 2015 MERS outbreak in South Korea.

Severity group No. (%)
Age, y, mean + SD No. associated spike genotypes
Men Women WT I529T D510G WT–I529T WT–I529T–D510G
I 3 (50.0) 3 (50.0) 54 + 13 1 2 1 1 1
II 9 (47.4) 10 (52.6) 46 + 11 0 10 2 6 1
III 8 (75.0) 4 (25.0) 48 + 12 3 4 0 4 1
IV 7 (63.6)  4 (36.4) 68 + 13 1 6 0 3 1

MERS, Middle East respiratory syndrome; WT, wild-type.

Main Article

1These first authors contributed equally to this article.

2These authors were co-principal investigators.

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