TY - JOUR AU - Multani, Ashrit AU - Meer, Aabed AU - Smith, Darvin AU - Kheraj, Malika AU - Plowey, Edward AU - Blackburn, Brian T1 - Diagnosis of Chagasic Encephalitis by Sequencing of 28S rRNA Gene T2 - Emerging Infectious Disease journal PY - 2019 VL - 25 IS - 7 SP - 1370 SN - 1080-6059 AB - We report a case of chagasic encephalitis diagnosed by 28S rRNA sequencing. The diagnosis of chagasic encephalitis is challenging, given the broad differential diagnosis for central nervous system lesions in immunocompromised patients and low sensitivity of traditional diagnostics. Sequencing should be part of the diagnostic armamentarium for potential chagasic encephalitis. KW - chagasic encephalitis KW - Chagas disease KW - Trypanosoma cruzi KW - parasites KW - protozoa KW - meningitis/encephalitis KW - ribosomal RNA sequencing KW - HIV/AIDS KW - immunocompromised KW - 28S rRNA gene KW - rRNA sequencing KW - HIV/AIDS and other retroviruses DO - 10.3201/eid2507.180285 UR - https://wwwnc.cdc.gov/eid/article/25/7/18-0285_article ER - End of Reference