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Volume 25, Number 8—August 2019
Dispatch

Case Series Study of Melioidosis, Colombia

José Y. RodríguezComments to Author , Soraya E. Morales-López, Gerson J. Rodríguez, Carlos A. Álvarez-Moreno, Kelin Esquea, Heidy Pinzon, Luis R. Ramirez, Lilian Moreno, Walter Ocampo, and Martha L. Cepeda
Author affiliations: Hospital Rosario Pumarejo de López, Valledupar, Colombia (J.Y. Rodríguez); Centro de Investigaciones Microbiológicas del Cesar (CIMCE), Valledupar (J.Y. Rodríguez, G.J. Rodríguez); Clínica Laura Daniela, Valledupar (J.Y. Rodríguez, K. Esquea); Clínica Médicos LTDA, Valledupar (J.Y. Rodríguez, H. Pinzon); Laboratorios Nancy Flórez García S.A.S., Valledupar (S.E. Moralez-López); Universidad Popular del Cesar, Valledupar (S.E. Moralez-López); Universidad Nacional de Colombia, Bogotá, Colombia (C.A. Álvarez-Moreno); Clínica Universitaria Colombia, Clínicas Colsanitas, Bogotá (C.A. Álvarez-Moreno); Grupo de Investigaciones Microbiológicas del Cesar, Valledupar (L.R. Ramirez, L. Moreno); Corporación CorpoGen, Bogotá (W. Ocampo, M.L. Cepeda)

Main Article

Table 1

Epidemiologic and demographic characteristics, underlying conditions, clinical manifestations and outcomes of patients with melioidosis in the Caribbean coast region of Colombia*

Patient no. Patient age, y/ sex Medical history and risk factors Clinical manifestation Type of sample Empirical treatment Appropriate treatment (duration) ICU Outcome Relapse
1
72/M
Diabetes, arterial hypertension
Bacteremic pneumonia
Blood culture, urine culture, endotracheal aspirate
TZP + CLR
IP: MER + TMP/SMX (14 d); EP: NA
Yes
Died
NA
2
60/F
Diabetes, arterial hypertension,
minor head injury with open scalp wound
Bacteremic SSTI
Wound secretion, blood culture
CFZ + CLI
IP: MER (10 d); EP: TMP/SMX (3 mo)
No
Alive
No
3
49/M
Diabetes, leprosy, erythema nodosum leprosum, chronic use of steroids
Bacteremic pneumonia
Blood culture, urine culture, sputum culture
TZP + CLR
IP: MER (10 d); EP: TMP/SMX (6 mo)
No
Alive
No
4
71/M
Arterial hypertension, multiple myeloma, bone marrow transplant, chronic use of steroids and thalidomide
Bacteremic pneumonia
Blood culture
TZP + DOX
IP: MER (14 d); EP: TMP/SMX (3 mo)
No
Alive
No
5
66/M
Diabetes,
arterial hypertension
Bacteremic pneumonia
Blood culture, endotracheal aspirate
TZP
NA
Yes
Died
NA
6
56/M
Diabetes, chronic renal failure
UTI
Urine culture
TZP
IP: MER (10 d); EP: TMP/SMX (3 mo)
No
Alive
At 6 mo: bacteremia, UTI, SSTI
7 54/M Tibia and fibula open fracture SSTI Wound secretion, blood culture CFZ + CLI IP: MER (10 d); EP: TMP/SMX (6 mo) No Alive No

*CFZ, cefazolin; CLI, clindamycin; CLR, clarithromycin; DOX, doxycycline; EP, eradication phase; IP, intensive phase; MER, meropenem; NA, not available; SSTI, skin and soft tissue infection; TMP/SMX, trimethoprim/sulfamethoxazole; TZP, piperacillin/tazobactam; UTI, urinary tract infection.

Main Article

Page created: July 16, 2019
Page updated: July 16, 2019
Page reviewed: July 16, 2019
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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