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Volume 25, Number 8—August 2019
Dispatch

Wild-Type Yellow Fever Virus RNA in Cerebrospinal Fluid of Child

Paula E.S. Marinho1, Pedro P.M. Alvarenga1, Ana P.C. Crispim, Talitah M.S. Candiani, Alice M. Alvarenga, Isabela M. Bechler, Pedro A. Alves, Fabio P. Dornas, Danilo B. de Oliveira, Aline A. Bentes, Paulo P. Christo, and Erna G. KroonComments to Author 
Author affiliations: Universidade Federal de Minas Gerais, Belo Horizonte, Brazil (P.E.S. Marinho, A.P.C. Crispim, A.A. Bentes, E.G. Kroon); Hospital Infantil João Paulo II, Belo Horizonte (P.P.M. Alvarenga, T.M.S. Candiani, A.M. Alvarenga, I.M. Bechler, A.A. Bentes); Instituto René Rachou, Belo Horizonte (P.A. Alves); Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina, Brazil (F.P. Dornas, D.B. de Oliveira); Instituto de Ensino e Pesquisa Santa Casa de Belo Horizonte, Belo Horizonte (P.P. Christo)

Main Article

Figure 1

Illness timeline and phylogenetic testing in case of child with wild-type yellow fever virus RNA in CSF, Brazil, 2017. A) Timeline of symptoms, ambulatory procedures, and laboratory results. B) Phylogenetic tree of yellow fever viruses. The tree was constructed by using the maximum-likelihood method and the Tamura-Nei model in MEGA 7.0 software (https://www.megasoftware.net). Numbers to the left of nodes are bootstrap values (1,000 replicates). Sequences were compared with sequences in GenBank;

Figure 1. Illness timeline and phylogenetic testing in case of child with wild-type yellow fever virus RNA in CSF, Brazil, 2017. A) Timeline of symptoms, ambulatory procedures, and laboratory results. B) Phylogenetic tree of yellow fever viruses. The tree was constructed by using the maximum-likelihood method and the Tamura-Nei model in MEGA 7.0 software (https://www.megasoftware.net). Numbers to the left of nodes are bootstrap values (1,000 replicates). Sequences were compared with sequences in GenBank; black dot indicates sequence isolated in this study. This sequence was deposited in GenBank (accession no. 771_2017_CSF_NS5 MK450540). Scale bar indicates nucleotide substitutions per site. CSF, cerebrospinal fluid.

Main Article

1These authors contributed equally to this article.

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Page updated: July 16, 2019
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