TY - JOUR AU - Kim, So Yeon AU - Lee, Jaehyeon AU - Sung, Heungsup AU - Lee, Hyukmin AU - Han, Myung Guk AU - Yoo, Cheon Kwon AU - Lee, Sang Won AU - Hong, Ki Ho T1 - Pooling Upper Respiratory Specimens for Rapid Mass Screening of COVID-19 by Real-Time RT-PCR T2 - Emerging Infectious Disease journal PY - 2020 VL - 26 IS - 10 SP - 2469 SN - 1080-6059 AB - To validate the specimen-pooling strategy for real-time reverse transcription PCR detection of severe acute respiratory syndrome coronavirus 2, we generated different pools including positive specimens, reflecting the distribution of cycle threshold values at initial diagnosis. Cumulative sensitivities of tested pool sizes suggest pooling of <6 specimens for surveillance by this method. KW - coronavirus disease KW - SARS-CoV-2 KW - severe acute respiratory syndrome coronavirus 2 KW - severe acute respiratory syndrome KW - SARS KW - viruses KW - respiratory infections KW - zoonoses KW - COVID-19 KW - SARS-related coronavirus KW - SAR-CoV-2 KW - real-time PCR KW - reverse transcription PCR KW - specimen pooling KW - South Korea DO - 10.3201/eid2610.201955 UR - https://wwwnc.cdc.gov/eid/article/26/10/20-1955_article ER - End of Reference