Figure 4. Hepatocyte growth factor plasma levels in patients with acute LF and liver function tests in acute LF cases, Sierra Leone, 2015–2018. A) HGF was positively correlated with total bilirubin (n = 23), alkaline phosphatase (n = 26), AST (n = 26), and ALT (n = 27). B) HGF levels in acute LF patients were statistically significantly higher (***p = 0.0005) in patients who died (n = 14) than those who survived (n = 7), and a statistically significant positive correlation between HGF and LASV antigen was observed in LF patients (n = 22). Dashed lines and gray shading indicate limits of detection. ALT, alanine aminotransferase; AST, aspartate aminotransferase; D, died; HGF, hepatocyte growth factor; LF, Lassa fever; LASV-Ag, Lassa fever virus antigen; S, survived.