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Volume 26, Number 11—November 2020
Research

Streptococcus pneumoniae Serotype 12F-CC4846 and Invasive Pneumococcal Disease after Introduction of 13-Valent Pneumococcal Conjugate Vaccine, Japan, 2015–2017

Satoshi NakanoComments to Author , Takao Fujisawa, Yutaka Ito, Bin Chang, Yasufumi Matsumura, Masaki Yamamoto, Shigeru Suga, Makoto Ohnishi, and Miki Nagao
Author affiliations: Kyoto University Graduate School of Medicine, Kyoto, Japan (S. Nakano, Y. Matsumura, M. Yamamoto, M. Nagao); National Hospital Organization Mie National Hospital, Tsu, Japan (T. Fujisawa, S. Suga); Nagoya City University Graduate School of Medical Science, Nagoya, Japan (Y. Ito); National Institute of Infectious Diseases, Tokyo, Japan (B. Chang, M. Ohnishi)

Main Article

Figure 1

Recombination-free maximum-likelihood tree of Streptococcus pneumoniae serotype 12F-CC4846 isolates in Japan, created by using Gubbins (27). Two clusters were generated: 1 comprised only sequence type (ST) 4846 isolates and the other comprised only ST6945 isolates. All isolates had pbp1a-13. The pbp2x type “others” included pbp2x-JP23, pbp2x-JP58, and pbp2x-JP59. The geographic locations of the described regions in this figure are shown in the Appendix. The numbers on the branches indicate bootstrap values. SNP, single-nucleotide polymorphism; ST, sequence type.

Figure 1. Recombination-free maximum-likelihood tree of Streptococcus pneumoniae serotype 12F-CC4846 isolates in Japan, created by using Gubbins (27). Two clusters were generated: 1 comprised only sequence type (ST) 4846 isolates and the other comprised only ST6945 isolates. All isolates had pbp1a-13. The pbp2x type “others” included pbp2x-JP23, pbp2x-JP58, and pbp2x-JP59. The geographic locations of the described regions in this figure are shown in the Appendix. The numbers on the branches indicate bootstrap values. SNP, single-nucleotide polymorphism; ST, sequence type.

Main Article

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