Volume 26, Number 11—November 2020
CME ACTIVITY - Research
Phage-Mediated Immune Evasion and Transmission of Livestock-Associated Methicillin-Resistant Staphylococcus aureus in Humans
|Variant||Phylogenetic cluster†||IEC type||Integration site‡||tarP||Isolate origin||Household ID||Farm ID|
|I||A||B||0723–0724||–||1 pig farm employee and 4 household members||H02||F01|
|II||B||E||2238||–||1 pig farm employee and 1 household member||H30||F01|
|III||C||B||2059 (hlb)||–||1 pig farm employee and 3 household members||H63||F04|
|IV||D||B||2591 (cidA)||–||1 pig farm employee||H51||F07|
|V||E||F||2059 (hlb)||+||1 pig veterinarian||H46||None|
|VI||E||F||2644||+||1 mink farm employee and 3 household members||H49||F21|
*Allocation of ΦSa3int prophages into variants (ΦSa3int-I to ΦSa3int-VI) was based on their phylogenetic relationship, IEC type, and chromosomal integration site. CC, clonal complex; ID, identification; IEC, immune evasion cluster; NA, not applicable; –, negative, +, positive. †Phylogenetic clusters are illustrated in Figure 1. ‡Numbers refer to annotated genes in reference strain S0385 (GenBank accession no. NC_017333).
1These senior authors contributed equally to this article.