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Volume 26, Number 11—November 2020

Phage-Mediated Immune Evasion and Transmission of Livestock-Associated Methicillin-Resistant Staphylococcus aureus in Humans

Raphael N. Sieber, Tinna R. Urth, Andreas Petersen, Camilla H. Møller, Lance B. Price, Robert L. Skov, Anders R. Larsen, Marc Stegger1, and Jesper Larsen1Comments to Author 
Author affiliations: Statens Serum Institut, Copenhagen, Denmark (R.N. Sieber, T.R. Urth, A. Petersen, C.H. Møller, R.L. Skov, A.R. Larsen, M. Stegger, J. Larsen); Translational Genomics Research Institute, Flagstaff, Arizona, USA (L.B. Price, M. Stegger); George Washington University, Washington, DC, USA (L.B. Price)

Main Article

Table 2

Patient characteristics and presence of IEC among livestock-associated methicillin-resistant Staphylococcus aureus CC398 cases and isolates, North Denmark Region, Denmark*

Patient group No. isolates Male:female ratio Median age, y (range) % IEC No. IEC-related excess cases (% all cases) Prevalence ratio (95% CI) p value
Patients with livestock contact
Direct contact 727 3.2 33 (0–93) 3.4 Referent Referent Referent
Indirect contact
22 (0–91)
7 (2.8)
1.82 (0.99–3.31)
Patients with CO infection
52 (0–98)
14 (3.6)
2.05 (1.21–3.46)
Patients with HO/HACO infection 179 1.1 66 (0–97) 11 14 (7.7) 3.25 (1.85–5.65) 0.0001

*CC, clonal complex; CO, community-onset; HACO, healthcare-associated community-onset; HO, healthcare-onset; IEC, immune evasion cluster.

Main Article

1These senior authors contributed equally to this article.

Page created: September 11, 2020
Page updated: October 15, 2020
Page reviewed: October 15, 2020
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