Acquisition of Plasmid with Carbapenem-Resistance Gene blaKPC2 in Hypervirulent Klebsiella pneumoniae, Singapore
Yahua Chen, Kalisvar Marimuthu, Jeanette Teo, Indumathi Venkatachalam, Benjamin Pei Zhi Cherng, Liang De Wang, Sai Rama Sridatta Prakki, Weizhen Xu, Yi Han Tan, Lan Chi Nguyen, Tse Hsien Koh, Oon Tek Ng, and Yunn-Hwen Gan
Author affiliations: National University of Singapore, Singapore (Y. Chen, Y.H. Tan, L.C. Nguyen, Y.-H. Gan); National Centre for Infectious Diseases, Singapore (K. Marimuthu, L.D. Wang, S.R.S. Prakki, W. Xu, O.T. Ng); Tan Tock Seng Hospital, Singapore (K. Marimuthu, O.T. Ng); National University Hospital, Singapore (J. Teo); Singapore General Hospital, Singapore (I. Venkatachalam, B.P.Z. Cherng, T.H. Koh); Nanyang Technological University, Singapore (O.T. Ng)
Figure 4. Maximum-likelihood analysis of pKPC2 plasmids from carbapenem-resistant hypervirulent Klebsiella pneumoniae isolates, Singapore, 2013–2015. pKPC2_494 was used as reference. Labels indicate isolate no._patient no._K serotype_sequence type. Days between isolate collection are indicated. Scale bar indicates nucleotide changes per base pair. KPC, Klebsiella pneumoniae carbapenemase; ST, sequence type.
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