Figure 2. Phylogenetic inference of Orthopoxvirus genus based on the A56R hemagglutinin gene. Nucleotide sequences of 829 bp representing the different species were aligned and used for Bayesian inference (Appendix). Black diamonds indicate previously reported sequences of VACV in Colombia; red diamond indicates sequence from the strain from the patient in this study (POX0009). GenBank accession numbers are provided for reference sequences. CPXV, cowpox virus; MPXV, monkeypox virus; VACV, vaccinia virus; VARV, variola virus.