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Volume 26, Number 4—April 2020
Dispatch

Ebola Virus Neutralizing Antibodies in Dogs from Sierra Leone, 2017

Kerstin Fischer, Roland Suluku, Sarah Katharina Fehling, Juliet Jabaty, Bashiru Koroma, Thomas Strecker, Martin H. Groschup, and Sandra DiederichComments to Author 
Author affiliations: Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany (K. Fischer, M.H. Groschup, S. Diederich); Njala University, Bo, Sierra Leone (R. Suluku, B. Koroma); Philipps University of Marburg, Marburg, Germany (S.K. Fehling, T. Strecker); Sierra Leone Agricultural Research Institute, Freetown, Sierra Leone (J. Jabaty)

Main Article

Figure 2

Analysis of dog serum samples in VNTs for study of EBOV neutralizing antibodies in dogs, Moyamba District, Sierra Leone, 2017. Comparison of dog serum titers obtained in VNTs was based on live EBOV (variant Mayinga) and EBOV trVLP. For VNT using authentic EBOV, serum samples with a titer <1:8 (vertical solid line) are counted as negative; samples with a neutralizing titer >1:8 are considered positive. For trVLP-based VNT, titers equal to 1:16 (vertical dashed line) are counted as positive.

Figure 2. Analysis of dog serum samples (circles) in VNTs for study of EBOV neutralizing antibodies in dogs, Moyamba District, Sierra Leone, 2017. Comparison of dog serum titers obtained in VNTs was based on live EBOV (variant Mayinga) and EBOV trVLP. For VNT using authentic EBOV, serum samples with a titer <1:8 (horizontal solid line) are counted as negative; samples with a neutralizing titer >1:8 are considered positive. For trVLP-based VNT, titers equal to 1:16 (horizontal dashed line) are counted as positive. EBOV, Ebola virus; trVLP, transcription and replication competent virus-like particles; VNTs, virus neutralization tests.

Main Article

Page created: March 17, 2020
Page updated: March 17, 2020
Page reviewed: March 17, 2020
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