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Volume 26, Number 5—May 2020
Synopsis

Epidemiology of Tick-Borne Relapsing Fever in Endemic Area, Spain

María Carmen DomínguezComments to Author , Salvador Vergara, María Carmen Gómez, and María Esther Roldán
Author affiliations: Hospital de la Merced, Osuna, Spain (M.C. Domínguez, M.C. Gómez, M.E. Roldán); Hospital del Tomillar, Seville, Spain (S. Vergara)

Main Article

Table 2

Main symptoms, signs, and analytical findings of 98 patients with tick-borne relapsing fever, Spain*

Variable Value
Symptoms
Fever >38.5°C 97 (99)
Headache 58 (59)
Vomiting 34 (34.7)
Arthralgia 29 (30)
Abdominal pain 28 (28.6)
Myalgia 28 (28.6)
Chills 23 (23.6)
Diarrhea
6 (6.1)
Signs
Meningeal signs 7 (7.1)
Splenomegaly 7 (7.1)
Hepatomegaly 6 (6.1)
Exanthema 4 (4.1)
Jaundice 3 (3.1)
Petechiae 2 (2)
Conjunctival injection
2 (2)
Analytical findings
Median platelet count, × 103/mm3 (IQR) 63.5 (45.7–87.5)
Thrombocytopenia, platelets <13 × 104/mm3 91 (92.9)
Hemoglobin, g/dL (IQR) 13.1 (11.8–14.2)
Anemia 32 (32.6)
Leukocytes, ×103/mm3 (IQR) 7.9 (6.6–9.8)
Leukocytosis, >11,500/mm3 10 (10.2)
Neutrophils, median (IQR) 79.9 (74.5–86.4)
Neutrophilia, neutrophils >65% 91 (92.9)
Prothrombin activity, median (IQR) 77 (70–87)
Decreased prothrombin activity, <70% 7 (13.7)
Median INR (IQR) 1.2 (1.1–1.3)
INR elevation, >1.51 7 (13.7)
SGOT, U/L (IQR) 25 (20–35)
SGOT elevation, >37 U/L 15 (21.7)
SGPT, U/L (IQR) 25 (17–41)
SGPT elevation, >40 U/L 10 (23.3)
Total bilirubin, mg/dL (IQR) 1.1 (0.6–1.9)
Elevated bilirubin, >1.2 mg/dL 37 (37.8)
Lactate dehydrogenase, U/L(IQR) 397.5 (320.7–481.7)
Elevated LDH, >460 U/L 16 (30.8)
Creatinine, mg/dL (IQR) 0.94 (0.79–1.15)
Creatinine elevation, >1.2 mg/dL 15 (15.3)
Creatine kinase, U/L (IQR) 41 (27–75)
Elevated creatine kinase, >195 U/L 3 (14)
C-reactive protein, mg/L (IQR) 254.5 (218.2–335.3)
Elevated C-reactive protein, >5 mg/L
98 (100)
*Values are no. (%) except as indicated. INR, international normalized ratio; IQR, interquartile range; SGOT, serum glutamic-oxaloacetic transaminase; SGPT, serum glutamic-pyruvic transaminase.

Main Article

Page created: April 16, 2020
Page updated: April 16, 2020
Page reviewed: April 16, 2020
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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