TY - JOUR
AU - Raja, Thamayanthi Nada
AU - Hu, Ting Huey
AU - Kadir, Khamisah Abdul
AU - Mohamad, Dayang Shuaisah Awang
AU - Rosli, Nawal
AU - Wong, Lolita Lin
AU - Hii, King Ching
AU - Simon Divis, Paul Cliff
AU - Singh, Balbir
T1 - Naturally Acquired Human Plasmodium cynomolgi and P. knowlesi Infections, Malaysian Borneo
T2 - Emerging Infectious Disease journal
PY - 2020
VL - 26
IS - 8
SP - 1801
SN - 1080-6059
AB - To monitor the incidence of Plasmodium knowlesi infections and determine whether other simian malaria parasites are being transmitted to humans, we examined 1,047 blood samples from patients with malaria at Kapit Hospital in Kapit, Malaysia, during June 24, 2013–December 31, 2017. Using nested PCR assays, we found 845 (80.6%) patients had either P. knowlesi monoinfection (n = 815) or co-infection with other Plasmodium species (n = 30). We noted the annual number of these zoonotic infections increased greatly in 2017 (n = 284). We identified 6 patients, 17–65 years of age, with P. cynomolgi and P. knowlesi co-infections, confirmed by phylogenetic analyses of the Plasmodium cytochrome c oxidase subunit 1 gene sequences. P. knowlesi continues to be a public health concern in the Kapit Division of Sarawak, Malaysian Borneo. In addition, another simian malaria parasite, P. cynomolgi, also is an emerging cause of malaria in humans.
KW - Malaria
KW - zoonosis
KW - Plasmodium cynomolgi
KW - Plasmodium knowlesi
KW - parasitic diseases
KW - Malaysian Borneo
KW - zoonoses
KW - parasites
DO - 10.3201/eid2608.200343
UR - https://wwwnc.cdc.gov/eid/article/26/8/20-0343_article
ER - End of Reference