TY - JOUR AU - Chu, Victoria AU - Freeman-Ponder, Brandi AU - Lindquist, Scott AU - Spitters, Christopher AU - Kawakami, Vance AU - Dyal, Jonathan AU - Clark, Shauna AU - Bruce, Hollianne AU - Duchin, Jeffrey AU - DeBolt, Chas AU - Podczervinski, Sara AU - D’Angeli, Marisa AU - Pettrone, Kristen AU - Zacks, Rachael AU - Vahey, Grace AU - Holshue, Michelle AU - Lang, Misty AU - Burke, Rachel AU - Rolfes, Melissa AU - Marlow, Mariel AU - Midgley, Claire AU - Lu, Xiaoyan AU - Lindstrom, Stephen AU - Hall, Aron AU - Fry, Alicia AU - Thornburg, Natalie AU - Gerber, Susan AU - Pillai, Satish AU - Biggs, Holly T1 - Investigation and Serologic Follow-Up of Contacts of an Early Confirmed Case-Patient with COVID-19, Washington, USA T2 - Emerging Infectious Disease journal PY - 2020 VL - 26 IS - 8 SP - 1671 SN - 1080-6059 AB - We describe the contact investigation for an early confirmed case of coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in the United States. Contacts of the case-patient were identified, actively monitored for symptoms, interviewed for a detailed exposure history, and tested for SARS-CoV-2 infection by real-time reverse transcription PCR (rRT-PCR) and ELISA. Fifty contacts were identified and 38 (76%) were interviewed, of whom 11 (29%) reported unprotected face-to-face interaction with the case-patient. Thirty-seven (74%) had respiratory specimens tested by rRT-PCR, and all tested negative. Twenty-three (46%) had ELISA performed on serum samples collected ≈6 weeks after exposure, and none had detectable antibodies to SARS-CoV-2. Among contacts who were tested, no secondary transmission was identified in this investigation, despite unprotected close interactions with the infectious case-patient. KW - COVID-19 KW - SARS-CoV-2 KW - contact tracing KW - serology KW - viruses KW - respiratory infections KW - coronavirus KW - 2019 novel coronavirus disease KW - severe acute respiratory syndrome coronavirus 2 KW - zoonoses KW - coronavirus disease DO - 10.3201/eid2608.201423 UR - https://wwwnc.cdc.gov/eid/article/26/8/20-1423_article ER - End of Reference