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Volume 26, Number 9—September 2020

Heterogeneity of Dengue Illness in Community-Based Prospective Study, Iquitos, Peru

William H. Elson, Robert C. Reiner, Crystyan Siles, Isabel Bazan, Stalin Vilcarromero, Amy R. Riley-Powell, Ania B. Kawiecki, Helvio Astete, Robert D. Hontz, Chris M. Barker, Gonzalo M. Vazquez-Prokopec, Amy C. Morrison, Thomas W. Scott, John P. Elder, Alan L. Rothman, and Valerie A. Paz-Soldan
Author affiliations: University of California Davis, Davis, California, USA (W.H. Elson, A.B. Kawiecki, C.M. Barker, A.C. Morrison, T.W. Scott); University of Washington School of Medicine, Seattle, Washington, USA (R.C. Reiner); US Naval Medical Research Unit No. 6, Lima and Iquitos, Peru (C. Siles, I. Bazan, S. Vilcarromero, H. Astete, R.D. Hontz, A.C. Morrison); University of Sussex, Brighton, UK (A.R. Riley-Powell); Tulane School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA (A.R. Riley-Powell, V.A. Paz-Soldan); Emory University, Atlanta, Georgia, USA (G.M. Vazquez-Prokopec); San Diego State University, San Diego, California, USA (J.P. Elder); University of Rhode Island, Providence, Rhode Island, USA (A.L. Rothman)

Main Article

Table 2

Effect of symptom intensity on reporting of major activity change for participants tested for heterogeneity of dengue illness in community-based prospective study, Iquitos, Peru

Symptom Odds ratio (95% CI)* Δ-AIC†
Malaise 1.36 (1.25–1.48) 42.1
Weakness 1.48 (1.36–1.63) 35.8
Fever 1.28 (1.19–1.38) 20.8
Abdominal 1.34 (1.22–1.48) 9.9
Body pain 1.32 (1.22–1.43) 9.1
Headache 1.27 (1.17–1.37) 9.0
Chills 1.31 (1.21–1.43) 3.3
Muscle pain 1.25 (1.15–1.35) 2.7
Joint pain 1.23 (1.13–1.34) −0.0
Retroorbital pain 1.11 (1.03–1.2) −0.1
Sore throat 1.02 (0.87–1.18) −0.5
Bone pain 1.24 (1.15–1.36) −1.4

*Shown is the increase in odds of reporting a major activity change when symptom intensity is increased by 1 point for each of the 12 symptoms.
†Δ-AIC, difference in Akaike Information Criteria between models by using binary symptom presence versus symptom intensity (0–10) as a predictor of major activity change. A positive Δ-AIC favors the use of intensity over presence of symptom alone.

Main Article

Page created: June 03, 2020
Page updated: August 18, 2020
Page reviewed: August 18, 2020
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