TY - JOUR AU - Adachi, Takuya AU - Chong, Ja-Mun AU - Nakajima, Noriko AU - Sano, Masahiro AU - Yamazaki, Jun AU - Miyamoto, Ippei AU - Nishioka, Haruka AU - Akita, Hidetaka AU - Sato, Yuko AU - Kataoka, Michiyo AU - Katano, Harutaka AU - Tobiume, Minoru AU - Sekizuka, Tsuyoshi AU - Itokawa, Kentaro AU - Kuroda, Makoto AU - Suzuki, Tadaki T1 - Clinicopathologic and Immunohistochemical Findings from Autopsy of Patient with COVID-19, Japan T2 - Emerging Infectious Disease journal PY - 2020 VL - 26 IS - 9 SP - 2157 SN - 1080-6059 AB - An autopsy of a patient in Japan with coronavirus disease indicated pneumonia lung pathology, manifested as diffuse alveolar damage. We detected severe acute respiratory syndrome coronavirus 2 antigen in alveolar epithelial cells and macrophages. Coronavirus disease is essentially a lower respiratory tract disease characterized by direct viral injury of alveolar epithelial cells. KW - COVID-19 KW - SARS-CoV-2 KW - cruise KW - autopsy KW - diffuse alveolar damage KW - immunohistochemistry KW - electron microscopy KW - next generation sequencing KW - coronavirus disease KW - severe acute respiratory syndrome coronavirus 2 KW - viruses KW - respiratory infections KW - zoonoses KW - next-generation sequencing KW - Japan DO - 10.3201/eid2609.201353 UR - https://wwwnc.cdc.gov/eid/article/26/9/20-1353_article ER - End of Reference