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Volume 26, Number 9—September 2020

Encephalopathy and Encephalitis Associated with Cerebrospinal Fluid Cytokine Alterations and Coronavirus Disease, Atlanta, Georgia, USA, 2020

Karima Benameur1Comments to Author , Ankita Agarwal1, Sara C. Auld, Matthew P. Butters, Andrew S. Webster, Tugba Ozturk, J. Christina Howell, Leda C. Bassit, Alvaro Velasquez, Raymond F. Schinazi, Mark E. Mullins, and William T. Hu
Author affiliations: Emory University School of Medicine, Atlanta, Georgia, USA

Main Article


Characteristics of 3 patients with coronavirus disease and neurologic complications, Atlanta, Georgia, USA, 2020*

Characteristic Patient 1 Patient 2 Patient 3
Neurologic findings
Encephalopathy Coma Moderate Mild
Brainstem reflexes affected All Corneal gag Oculocephalic
Myoclonus None Arms All limbs
Withdrawal to pain
CSF findings, reference value
Appearance, clear Cloudy Clear Clear
Opening pressure, 10–20 cm H2O
Nucleated cells
Total, 0–5/μL 115 1 0
% Neutrophils, 0%–6% 51 75 0
% Lymphocytes, 40%–80% 10 25 0
% Macrophages 15%–45%
Erythrocytes, 0/μL 3,426 29 7
Glucose, 40–70, mg/dL 40 111 88
Protein, 15–45, mg/dL >200 37 21

*CSF, cerebrospinal fluid.

Main Article

1These authors contributed equally to this article.

Page created: May 27, 2020
Page updated: August 18, 2020
Page reviewed: August 18, 2020
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