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Volume 26, Number 9—September 2020
Research

Retrospective Description of Pregnant Women Infected with Severe Acute Respiratory Syndrome Coronavirus 2, France

Alexandre J. VivantiComments to Author , Jérémie Mattern, Christelle Vauloup-Fellous, Jacques Jani, Luc Rigonnot, Larissa El Hachem, Agnès Le Gouez, Céline Desconclois, Imane Ben M’Barek, Jeanne Sibiude, Alexandra Benachi, Olivier Picone, and Anne-Gaël Cordier
Author affiliations: Antoine Béclère Hospital, Paris Saclay University, Clamart, France (A.J. Vivanti, J. Mattern, A. Le Gouez, C. Desconclois, A. Benachi); Paul Brousse Hospital, Paris Saclay University, Villejuif, France (C. Vauloup-Fellous); University Hospital Brugmann, Université Libre de Bruxelles, Brussels, Belgium (J. Jani); Centre Hospitalier Sud-Francilien, Corbeil-Essonnes, France (L. Rigonnot, L. El Hachem); Bicêtre Hospital, Paris Saclay University, Le Kremlin-Bicêtre, France (I. Ben M’Barek, A.-G. Cordier); Louis Mourier Hospital, Paris University, Colombes, France (J. Sibiude, O. Picone)

Main Article

Table 3

Laboratory parameters at diagnosis according to medical referral for pregnant women with severe acute respiratory syndrome 2 infection, France*

Laboratory findings Non-ICU hospitalization, n = 90
ICU hospitalization, n = 10
p value
Median (IQR) No. (%) Median (IQR) No. (%)
Hemoglobin, g/dL 11.4 (10.5–12.2) 64 (66.7) 9.8 (9.3–11.3) 9 (90) 0.02
Platelet count, × 109/L 230 (162–273) 63 (70.0) 205 (164–271) 9 (90) 0.98
Leukocyte count, × 109 cells/L
7.2 (5.4–8.9)
63 (70.0)

6.6 (6.1–7.2)
9 (90)
0.68
Lymphocyte count, × 109 cells/L 1.15 (0.9–1.6) 58 (64.4) 0.77 (0.7–1) 9 (90) 0.01
Lymphocytopenia, <1.00 × 109 cells/L
NA
21/58 (36.2)†

NA
8/9 (88.9)†
0.008
Prothrombin time, % 100 (99–100) 53 (58.9) 100 (100–100) 7 (70) 0.61
aPPT, ratio 1.06 (1–1.2) 52 (57.8) 1.12 (1–1.4) 7 (70) 0.16
Prolonged aPPT ratio (>1.20) NA 13/53 (24.5)† NA 3/7 (43)† 0.38
Fibrinogen activity, g/L 4.8 (4–5.8) 45 (50.0) 5.1 (4.5–5.5) 6 (60) 0.73
AST, U/L 25 (20–35) 48 (53.3) 30 (22–59) 8 (80) 0.38
ALT, U/L 17 (11–32) 49 (54.4) 19 (12–48) 8 (80) 0.46
C-reactive protein, mg/L 23 (9–42) 53 (58.9) 27 (22–108) 8 (80) 0.15
Creatinine, μmol/L 47 (41–57) 45 (50.0) 50 (38–55) 7 (70) 0.94

*ALT, alanine aminotransferase; aPPT, activated partial thromboplastin time; AST, aspartate aminotransferase; ICU, intensive care unit; IQR, interquartile range; NA, not applicable.
†Per available results.

Main Article

Page created: July 02, 2020
Page updated: August 18, 2020
Page reviewed: August 18, 2020
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