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Volume 27, Number 1—January 2021
Research

Post–13-Valent Pneumococcal Conjugate Vaccine Dynamics in Young Children of Serotypes Included in Candidate Extended-Spectrum Conjugate Vaccines

Shalom Ben-Shimol, Noga Givon-Lavi, Leore Kotler, Bart Adriaan van der Beek, David Greenberg, and Ron DaganComments to Author 
Author affiliations: Ben-Gurion University of the Negev, Beer Sheva, Israel (S. Ben-Shimol, N. Givon-Lavi, L. Kotler, B.A. van der Beek, D. Greenberg, R. Dagan); Soroka University Medical Center, Beer Sheva (S. Ben-Shimol, N. Givon-Lavi, L. Kotler, D. Greenberg)

Main Article

Figure 1

Postvaccine dynamics of pneumococcal conjugate vaccines in children <24 months of age, Israel, July 2009–June 2017. A) Healthy children; B) children with non–LRTIs; C) children with lower respiratory infections; D) children with conjunctivitis; E) children with otitis media (isolates from middle ear fluid were tested); and F) children with invasive pneumococcal disease (isolates from blood and cerebrospinal fluid were tested). Data show VT13, VT20–13, and NVT20 as the proportion of each serotype of all pneumococcal isolates. p<0.05 for all comparisons comparing 2015–2017 versus 2009–2011, except for VT20–13 in conjunctivitis. LRTI, lower respiratory tract infection; NVT, nonvaccine serotype; VT, vaccine serotype.

Figure 1. Postvaccine dynamics of pneumococcal conjugate vaccines in children <24 months of age, Israel, July 2009–June 2017. A) Healthy children; B) children with non–LRTIs; C) children with lower respiratory infections; D) children with conjunctivitis; E) children with otitis media (isolates from middle ear fluid were tested); and F) children with invasive pneumococcal disease (isolates from blood and cerebrospinal fluid were tested). Data show VT13, VT20–13, and NVT20 as the proportion of each serotype of all pneumococcal isolates. p<0.05 for all comparisons comparing 2015–2017 versus 2009–2011, except for VT20–13 in conjunctivitis. LRTI, lower respiratory tract infection; NVT, nonvaccine serotype; VT, vaccine serotype.

Main Article

Page created: November 19, 2020
Page updated: December 21, 2020
Page reviewed: December 21, 2020
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