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Volume 27, Number 1—January 2021

Human Diversity of Killer Cell Immunoglobulin-Like Receptors and Human Leukocyte Antigen Class I Alleles and Ebola Virus Disease Outcomes

Tony Wawina-Bokalanga, Bert Vanmechelen, Valentine Lhermitte, Joan Martí-Carreras, Valentijn Vergote, Fara Raymond Koundouno, Joseph Akoi-Boré, Ruth Thom, Tom Tipton, Kimberley Steeds, Kéita Balla Moussa, Ablam Amento, Lies Laenen, Sophie Duraffour, Martin Gabriel, Paula Ruibal, Yper Hall, Mandy Kader-Kondé, Stephan Günther, Guy Baele, Cesar Muñoz-Fontela, Johan Van Weyenbergh, Miles W. Carroll, and Piet MaesComments to Author 
Author affiliations: KU Leuven, Leuven, Belgium (T. Wawina-Bokalanga, B. Vanmechelen, V. Lhermitte, J. Martí-Carreras, V. Vergote, L. Laenen, G. Baele, J. Van Weyenbergh, P. Maes); University Julius Nyerere of Kankan, Conakry, Guinea (F.R. Koudouno); Institut National de Santé Publique, Conakry (J. Akoi-Boré); Public Health England, Salisbury, UK (R. Thom, T. Tipton, K. Steeds, Y. Hall, M.W. Carroll); Centre d'Excellence de Formation et Recherche sur les Maladies Prioritaires en Guinée, Conakry (K.B. Moussa, A. Amento, M. Kader-Kondé); German Center for Infection Research, Hamburg-Lübeck-Borstel-Riems, Germany (S. Duraffour, M. Gabriel); Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany (S. Duraffour, M. Gabriel, P. Ruibal, S. Günther, C. Muñoz-Fontela)

Main Article

Table 3

Results from the multinomial logistic regression of human leukocyte antigen class I and killer cell immunoglobulin-like receptor genes in Ebola virus–infected patients, Guinea, 2015–2017*

Term p ≠ 0 β estimate SE Best model
2DL2 88.1 1.02 0.54 1.18
2DL5 59.1 −0.43 0.46 −0.65
KIR2DS4.0003 16.6 −0.08 0.20 (...)
HLA-B-Bw4-Thr 45.8 −0.38 0.48 (...)
HLA-B-Bw4-Ile 45.1 0.27 0.34 (...)

*Intercepts have been omitted for interpretation purposes. p ≠ 0 indicates the probability that the coefficient for a given predictor is not zero. Ellipses (...) represent predictors that were not present in the best model.

Main Article

Page created: October 16, 2020
Page updated: December 21, 2020
Page reviewed: December 21, 2020
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