TY - JOUR AU - Kontula, Keiju S.K. AU - Skogberg, Kirsi AU - Ollgren, Jukka AU - Järvinen, Asko AU - Lyytikäinen, Outi T1 - Population-Based Study of Bloodstream Infection Incidence and Mortality Rates, Finland, 2004–2018 T2 - Emerging Infectious Disease journal PY - 2021 VL - 27 IS - 10 SP - 2560 SN - 1080-6059 AB - We evaluated the incidence, outcomes, and causative agents of bloodstream infections (BSI) in Finland during 2004–2018 by using data from the national registries. We identified a total of 173,715 BSIs; annual incidence increased from 150 to 309 cases/100,000 population. BSI incidence rose most sharply among persons >80 years of age. The 1-month case-fatality rate decreased from 13.0% to 12.6%, but the 1-month all-cause mortality rate rose from 20 to 39 deaths/100,000 population. BSIs caused by Escherichia coli increased from 26% to 30% of all BSIs. BSIs caused by multidrug-resistant microbes rose from 0.4% to 2.8%, mostly caused by extended-spectrum β-lactamase-producing E. coli. We observed an increase in community-acquired BSIs, from 67% to 78%. The proportion of patients with severe underlying conditions rose from 14% to 23%. Additional public health and healthcare prevention efforts are needed to curb the increasing trend in community-acquired BSIs and antimicrobial drug–resistant E. coli. KW - bloodstream infections KW - incidence KW - case-fatality rates KW - mortality rates KW - community-acquired infections KW - healthcare-associated infections KW - antimicrobial resistance KW - bacteria KW - fungi KW - MRSA and other staphylococci KW - streptococci KW - Finland DO - 10.3201/eid2710.204826 UR - https://wwwnc.cdc.gov/eid/article/27/10/20-4826_article ER - End of Reference