TY - JOUR AU - Shukla, Bhavarth AU - Warde, Prem AU - Knott, Eric AU - Arenas, Sebastian AU - Pronty, Darryl AU - Ramirez, Reinaldo AU - Rego, Arely AU - Levy, Miriam AU - Zak, Martin AU - Parekh, Dipen AU - Ferreira, Tanira AU - Gershengorn, Hayley T1 - Bloodstream Infection Risk, Incidence, and Deaths for Hospitalized Patients during Coronavirus Disease Pandemic T2 - Emerging Infectious Disease journal PY - 2021 VL - 27 IS - 10 SP - 2588 SN - 1080-6059 AB - Hospital-acquired infections are emerging major concurrent conditions during the coronavirus disease (COVID-19) pandemic. We conducted a retrospective review of hospitalizations during March‒October 2020 of adults tested by reverse transcription PCR for severe acute respiratory syndrome coronavirus 2. We evaluated associations of COVID-19 diagnosis with risk for laboratory-confirmed bloodstream infections (LCBIs, primary outcome), time to LCBI, and risk for death by using logistic and competing risks regression with adjustment for relevant covariates. A total of 10,848 patients were included in the analysis: 918 (8.5%) were given a diagnosis of COVID-19, and 232 (2.1%) had LCBIs during their hospitalization. Of these patients, 58 (25%) were classified as having central line‒associated bloodstream infections. After adjusting for covariates, COVID-19‒positive status was associated with higher risk for LCBI and death. Reinforcement of infection control practices should be implemented in COVID-19 wards, and review of superiority and inferiority ranking methods by National Healthcare Safety Network criteria might be needed. KW - coronavirus disease KW - COVID-19 KW - pandemic KW - severe acute respiratory coronavirus 2 KW - SARS-CoV-2 KW - coronaviruses KW - viruses KW - respiratory infections KW - bloodstream infection risk KW - prone positioning KW - incidence KW - deaths KW - hospitalized patients KW - infection control KW - zoonoses DO - 10.3201/eid2710.210538 UR - https://wwwnc.cdc.gov/eid/article/27/10/21-0538_article ER - End of Reference