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Volume 27, Number 2—February 2021
Research

Role of Burkholderia pseudomallei–Specific IgG2 in Adults with Acute Melioidosis, Thailand

Panjaporn Chaichana, Kemajittra Jenjaroen, Suchintana Chumseng, Manutsanun Sumonwiriya, Patpong Rongkard, Barbara Kronsteiner, Prapit Teparrukkul, Direk Limmathurotsakul, Nicholas P.J. Day, Narisara Chantratita, and Susanna J DunachieComments to Author 
Author affiliations: Mahidol-Oxford Tropical Medicine Research Unit, Bangkok, Thailand (P. Chaichana, K. Jenjaroen, S. Chumseng, M. Sumonwiriya, P. Rongkard, D. Limmathurotsakul, N.P.J. Day, N. Chantratita, S.J. Dunachie); University of Oxford, Oxford, England (P. Rongkard, B. Kronsteiner, D. Limmathurotsakul, N.P.J. Day, S. Dunachie); Sunpasithiprasong Hospital, Ubon Ratchathani, Thailand (P. Teparrukkul)

Main Article

Figure 2

Comparison of antibody-dependent cellular phagocytosis (ADCP) activity between 82 survivors and 38 nonsurvivors of acute melioidosis, Thailand. ADCP activity was tested by using U937 (A) and THP-1 (B) human monocytic cell lines. Heat-inactivated serum samples were incubated with live fluorescein isothiocyanate–labeling Burkholderia pseudomallei before transfer to the cells, and the percentage of B. pseudomallei uptake by cells was analyzed by flow cytometer. We used the Mann-Whitney U test for statistical comparison.

Figure 2. Comparison of antibody-dependent cellular phagocytosis (ADCP) activity between 82 survivors and 38 nonsurvivors of acute melioidosis, Thailand. ADCP activity was tested by using U937 (A) and THP-1 (B) human monocytic cell lines. Heat-inactivated serum samples were incubated with live fluorescein isothiocyanate–labeling Burkholderia pseudomallei before transfer to the cells, and the percentage of B. pseudomallei uptake by cells was analyzed by flow cytometer. We used the Mann-Whitney U test for statistical comparison.

Main Article

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Page updated: January 23, 2021
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