Volume 27, Number 3—March 2021
Dispatch
Human Infection with Eurasian Avian-Like Swine Influenza A(H1N1) Virus, the Netherlands, September 2019
Table 1
Cross-reactivity in virus neutralization tests between isolates from a pig farmer and his pigs and reference swine H1N1, pH1N1, H1N2 and H3N2 viruses*
Virus | Subtype | H1 clade | Virus neutralization titer for swine antiserum† |
||||||
---|---|---|---|---|---|---|---|---|---|
swBe98 | swG10 | Ca09 | swG99 | swG12 | swFl98 | swG08 | |||
swBe98 | H1N1 | 1C.2 | 4,096 | 256 | 96 | 32 | <4 | <4 | <4 |
swG10 | H1N1 | 1C.2.1 | 48 | 768 | 12 | <4 | <4 | <4 | <4 |
Ca09 | pH1N1 | 1A.3.3.2 | 12 | 96 | 1,536 | <4 | <4 | <4 | <4 |
swG99 | H1N2 | 1B.1.2.1 | 6 | <4 | 4 | 1,024 | 768 | <4 | <4 |
swG12 | H1N2 | 1B.1.2.1 | <4 | <4 | 6 | 768 | 1,536 | <4 | <4 |
swFl98 | H3N2 | NA | <4 | <4 | 4 | <4 | <4 | 8,129 | 512 |
swG08 | H3N2 | NA | <4 | <4 | <4 | <4 | <4 | 3,072 | 768 |
Ne19 | H1N1v | 1C.2.2 | 128 | 64 | 8 | <4 | <4 | <4 | <4 |
swNe19 | H1N1 | 1C.2.2 | 256 | 384 | 1,536 | 8 | <4 | <4 | <4 |
*Ne19 indicates isolate from the farmer; swNe19 indicates the isolate from the pigs. Homologous titers are indicated in bold. H1N1v, H1N1 variant; NA, not applicable; pH1N1, influenza A(H1N1)pdm09; swBe98, A/swine/Belgium/1/98; swG10, A/swine/Gent/28/2010; Ca09, A/California/04/2009; swG99, A/swine/Gent/7625/99; swG12, A/swine/Gent/26/2012; swFl98, A/swine/Flanders/1/98; swG08, A/swine/Gent/172/2008; Ne19, A/Netherlands/Gent-193/2019; swNe19, A/swine/Netherlands/Gent-193/2019. †Swine antiserum was obtained by a double vaccination with whole inactivated virus vaccines.