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Volume 27, Number 3—March 2021

Isolate-Based Surveillance of Bordetella pertussis, Austria, 2018–2020

Adriana CabalComments to Author , Daniela Schmid, Markus Hell, Ali Chakeri, Elisabeth Mustafa-Korninger, Alexandra Wojna, Anna Stöger, Johannes Möst, Eva Leitner, Patrick Hyden, Thomas Rattei, Adele Habington, Ursula Wiedermann, Franz Allerberger, and Werner Ruppitsch
Author affiliations: Institute for Medical Microbiology and Hygiene, Austrian Agency for Health and Food Safety, Vienna, Austria (A. Cabal, D. Schmid, A. Chakeri, A. Stöger, F. Allerberger, W. Ruppitsch); MEDILAB, Teaching Laboratory of the Paracelsus Medical University, Salzburg, Austria (M. Hell, E. Mustafa-Korninger, A. Wojna); Centre for Public Health, Medical University Vienna, Vienna (A. Chakeri); MB-LAB Clinical Microbiology Laboratory, Innsbruck, Austria (J. Möst); Consultant Laboratory for Bordetella of the Robert Koch Institute, Medical University of Graz, Graz, Austria (E. Leitner); Centre for Microbiology and Environmental Systems Science, University of Vienna, Vienna (P. Hyden, T. Rattei); Children’s Health Ireland at Crumlin, Dublin, Ireland (A. Habington); Institute of Specific Prophylaxis and Tropical Medicine, Medical University of Vienna, Vienna (U. Wiedermann)

Main Article

Table 2

Genetic profiles of the 123 Bordetella pertussis isolates obtained through the B. pertussis isolate–based surveillance system, Austria, May 2018–May 2020*

Profile No. (%) B. pertussis vaccine antigen genes
ptxS1 ptxP prn fim2 fim3
Profile vaccine strain Tohama I 0 ptxS1-D ptxP-1 prn-1 fim2-1 fim3-1 NA
Profile A 64 (52.3) ptxS1-A ptxP-3 prn-2 fim2-1 fim3-1 (13,14)
Profile B 23 (18.7) ptxS1-A ptxP-3 prn-2–631^632STOP:T>- fim2-1 fim3-1 (15)
Profile C 20 (16.2) ptxS1-A ptxP-3 prn-2 fim2-1 fim3-2 (13,14)
Profile D 8 (6.50) ptxS1-A ptxP-3 prn-2–303+1326DEL fim2-1 fim3-1 (16)
Profile E 3† (2.44) ptxS1-A ptxP-3 prn-2-IS481–1613rev fim2-1 fim3-2 (13,14)
Profile F 2 (1.62) ptxS1-A ptxP-3 prn-2-IS481–1613rev fim2-1 fim3-1 (14)
Profile G 1 (0.8) ptxS1-A ptxP-3 prn-2- DEL1742–1839‡ fim2-1 fim3-2 This study
Profile H 1 (0.8) ptxS1-A ptxP-3 prn-2-STOP-T223C fim2-1 fim3-1 (14)
Profile I 1 (0.8) ptxS1-A ptxP-3 prn-2-C1273T fim2-1 fim3-1 (13,14)

*NA, not applicable.
†One isolate was sequence type 83.
‡This isolate showed an insertion longer than 200 bp in the prn gene combined with a partial deletion at positions nt 1742–1839.

Main Article

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