Clusters of Drug-Resistant Mycobacterium tuberculosis Detected by Whole-Genome Sequence Analysis of Nationwide Sample, Thailand, 2014–2017
Ditthawat Nonghanphithak, Angkana Chaiprasert, Saijai Smithtikarn, Phalin Kamolwat, Petchawan Pungrassami, Virasakdi Chongsuvivatwong, Surakameth Mahasirimongkol, Wipa Reechaipichitkul, Chaniya Leepiyasakulchai, Jody E. Phelan, David Blair, Taane G. Clark, and Kiatichai Faksri
Author affiliations: Khon Kaen University, Khon Kaen, Thailand (D. Nonghanphithak, W. Reechaipichitkul, K. Faksri); Mahidol University, Bangkok, Thailand (A. Chaiprasert, C. Leepiyasakulchai); Ministry of Public Health, Bangkok (S. Smithtikarn, P. Kamolwat, P. Pungrassami); Prince of Songkla University, Hat Yai, Songkhla, Thailand (V. Chongsuvivatwong); Ministry of Public Health, Nonthaburi, Thailand (S. Mahasirimongkol); London School of Hygiene and Tropical Medicine, London, UK (J.E. Phelan, T.G. Clark); James Cook University, Townsville, Queensland, Australia (D. Blair)
Figure 3. Geographic distribution of 13 major clades of drug-resistant tuberculosis in Thailand. A) The 13 clades are highlighted in the outer circle. Scale bar indicates the genetic distance proportional to the total number of single nucleotide polymorphisms. B–N) Each of the 13 major clades is associated with particular geographic regions, as shown. Mycobacterium canetti was used as an outgroup.
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