Clusters of Drug-Resistant Mycobacterium tuberculosis Detected by Whole-Genome Sequence Analysis of Nationwide Sample, Thailand, 2014–2017
Ditthawat Nonghanphithak, Angkana Chaiprasert, Saijai Smithtikarn, Phalin Kamolwat, Petchawan Pungrassami, Virasakdi Chongsuvivatwong, Surakameth Mahasirimongkol, Wipa Reechaipichitkul, Chaniya Leepiyasakulchai, Jody E. Phelan, David Blair, Taane G. Clark, and Kiatichai Faksri
Author affiliations: Khon Kaen University, Khon Kaen, Thailand (D. Nonghanphithak, W. Reechaipichitkul, K. Faksri); Mahidol University, Bangkok, Thailand (A. Chaiprasert, C. Leepiyasakulchai); Ministry of Public Health, Bangkok (S. Smithtikarn, P. Kamolwat, P. Pungrassami); Prince of Songkla University, Hat Yai, Songkhla, Thailand (V. Chongsuvivatwong); Ministry of Public Health, Nonthaburi, Thailand (S. Mahasirimongkol); London School of Hygiene and Tropical Medicine, London, UK (J.E. Phelan, T.G. Clark); James Cook University, Townsville, Queensland, Australia (D. Blair)
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Table 2
Demographic and other factors associated with clustering (≤11 SNP difference) of TB isolates, Thailand, 2014–2017*
Characteristic |
All isolates, n = 579 |
Clustering isolates
|
Odds ratio (95% CI) |
Isolates falling within clusters, n = 281 |
Nonclustering isolates, n = 298 |
Sex, n = 573 |
M |
419 (73.12) |
198 (70.71) |
221 (75.43) |
0.79 (0.54–1.14) |
F
|
154 (26.88)
|
82 (29.29)
|
72 (24.57)
|
1.27 (0.88–1.84)
|
Age, y, n = 508 |
Mean ± SD |
43.51 ± 14.68 |
42.02 ± 15.23 |
44.94 ± 14.03 |
NA |
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Page updated: February 21, 2021
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