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Volume 27, Number 3—March 2021

Clusters of Drug-Resistant Mycobacterium tuberculosis Detected by Whole-Genome Sequence Analysis of Nationwide Sample, Thailand, 2014–2017

Ditthawat Nonghanphithak, Angkana Chaiprasert, Saijai Smithtikarn, Phalin Kamolwat, Petchawan Pungrassami, Virasakdi Chongsuvivatwong, Surakameth Mahasirimongkol, Wipa Reechaipichitkul, Chaniya Leepiyasakulchai, Jody E. Phelan, David Blair, Taane G. Clark, and Kiatichai FaksriComments to Author 
Author affiliations: Khon Kaen University, Khon Kaen, Thailand (D. Nonghanphithak, W. Reechaipichitkul, K. Faksri); Mahidol University, Bangkok, Thailand (A. Chaiprasert, C. Leepiyasakulchai); Ministry of Public Health, Bangkok (S. Smithtikarn, P. Kamolwat, P. Pungrassami); Prince of Songkla University, Hat Yai, Songkhla, Thailand (V. Chongsuvivatwong); Ministry of Public Health, Nonthaburi, Thailand (S. Mahasirimongkol); London School of Hygiene and Tropical Medicine, London, UK (J.E. Phelan, T.G. Clark); James Cook University, Townsville, Queensland, Australia (D. Blair)

Main Article

Table 2

Demographic and other factors associated with clustering (≤11 SNP difference) of TB isolates, Thailand, 2014–2017*

Characteristic All isolates, n = 579 Clustering isolates
Odds ratio (95% CI)
Isolates falling within clusters, n = 281 Nonclustering isolates, n = 298
Sex, n = 573
M 419 (73.12) 198 (70.71) 221 (75.43) 0.79 (0.54–1.14)
154 (26.88)
82 (29.29)
72 (24.57)
1.27 (0.88–1.84)
Age, y, n = 508
Mean ± SD 43.51 ± 14.68 42.02 ± 15.23 44.94 ± 14.03 NA

*Values are no. (%) except as indicated. Bold type indicates statistical significance. NA, not applicable.

Main Article

Page created: December 29, 2020
Page updated: February 21, 2021
Page reviewed: February 21, 2021
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