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Volume 27, Number 4—April 2021

Genomic Characterizations of Clade III Lineage of Candida auris, California, USA

Travis K. Price, Ruel Mirasol, Kevin W. Ward, Ayrton J. Dayo, Evann E. Hilt, Sukantha Chandrasekaran, Omai B. Garner, Annabelle de St Maurice, and Shangxin YangComments to Author 
Author affiliation: University of California, Los Angeles, California, USA

Main Article

Table 2

Antifungal susceptibility results for Candida auris isolates, Los Angeles, California, USA, 2019–2020*

Antifungal MIC, μg/mL (interpretation)†
Amphotericin B 2 (R) 2 (R) 2 (R) 2 (R) 2 (R) 2 (R)
Fluconazole >64 (R) >64 (R) >64 (R) >64 (R) >64 (R) >64 (R)
Voriconazole 2 1 1 0.5 0.5 2
Itraconazole 1 1 0.5 0.25 0.25 1
Posaconazole 0.06 0.12 ≤0.03 ≤0.03 0.06 0.06
Anidulafungin 0.5 (S) 0.12 (S) 0.25 (S) 0.12 (S) 0.06 (S) 1 (S)
Caspofungin 0.5 (S) 0.12 (S) 0.5 (S) 0.5 (S) 0.12 (S) 0.5 (S)
Micafungin 0.25 (S) 0.25 (S) 0.25 (S) 0.12 (S) 0.25 (S) 0.25 (S)

*I, intermediate; R, resistant; S, susceptible.
†MIC testing was conducted on panels prepared in-house in accordance with Clinical and Laboratory Standards Institute guidelines ( Interpretive breakpoints were defined by the CDC Antifungal Susceptibility Testing and Interpretation guidelines for C. auris (, which were adapted from interpretive criteria for closely related Candida spp. Tentative breakpoints for the following antifungal drugs were: amphotericin B (>2 μg/mL), fluconazole (>32 μg/mL), anidulafungin (>4 μg/mL), caspofungin (>2 μg/mL), and micafungin (>4 μg/mL).

Main Article

Page created: March 11, 2021
Page updated: March 18, 2021
Page reviewed: March 18, 2021
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