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Volume 27, Number 4—April 2021
Research Letter

Experimental SARS-CoV-2 Infection of Bank Voles

Lorenz Ulrich1, Anna Michelitsch1, Nico Halwe1, Kerstin Wernike, Donata Hoffmann, and Martin BeerComments to Author 
Author affiliation: Friedrich-Loeffler-Institut, Greifswald–Insel Riems, Germany

Main Article

Table

RT-qPCR results of the swap sampling of all inoculated and contact bank voles*

Box Status Swab −1 dpi 2 dpi 4 dpi 8 dpi 12 dpi 16 dpi
Box 1 Inoculated Oral Neg 32.45 Neg Neg Neg Neg
Nasal Neg 32.29 Neg Neg Neg Neg
Rectal Neg Neg Neg Neg Neg Neg
Inoculated Oral Neg NA NA NA NA NA
Nasal Neg NA NA NA NA NA
Rectal Neg NA NA NA NA NA
Inoculated Oral Neg 32.09 28.16 Neg Neg Neg
Nasal Neg 31.72 34.03 Neg Neg Neg
Rectal Neg 36.54 36.39 Neg Neg Neg
Contact Oral Neg Neg Neg Neg Neg Neg
Nasal Neg Neg Neg Neg Neg Neg
Rectal Neg Neg Neg Neg Neg Neg
Collected feces
Neg
36.58
37.66
Neg
Neg
Neg
Box 2 Inoculated Oral Neg 29.40 32.41 NA NA NA
Nasal Neg 32.68 34.72 NA NA NA
Rectal Neg Neg Neg NA NA NA
Inoculated Oral Neg 30.46 32.54 Neg NA NA
Nasal Neg 32.30 Neg Neg NA NA
Rectal Neg 36.67 Neg Neg NA NA
Inoculated Oral Neg 32.72 37.07 Neg Neg Neg
Nasal Neg 34.74 Neg Neg Neg Neg
Rectal Neg Neg Neg Neg Neg Neg
Contact Oral Neg Neg Neg Neg Neg Neg
Nasal Neg Neg Neg Neg Neg Neg
Rectal Neg Neg Neg Neg Neg Neg
Collected feces
Neg
36.06
36.65
Neg
Neg
Neg
Box 3 Inoculated Oral Neg 30.98 Neg Neg NA NA
Nasal Neg 31.63 Neg Neg NA NA
Rectal Neg Neg Neg Neg NA NA
Inoculated Oral Neg 30.66 34.32 NA NA NA
Nasal Neg 34.52 Neg NA NA NA
Rectal Neg Neg 34.89 NA NA NA
Inoculated Oral Neg 32.64 Neg Neg Neg NA
Nasal Neg 35.46 Neg Neg Neg NA
Rectal Neg Neg Neg Neg Neg NA
Contact Oral Neg Neg Neg Neg Neg Neg
Nasal Neg Neg Neg Neg Neg Neg
Rectal Neg Neg Neg Neg Neg Neg
Collected feces
Neg 36.62 37.02 Neg Neg Neg

*Results are given in quantification cycle values. dpi, days postinoculation; NA, not applicable; Neg, negative.

Main Article

1These authors contributed equally to this article.

Page created: January 25, 2021
Page updated: March 18, 2021
Page reviewed: March 18, 2021
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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