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Volume 27, Number 5—May 2021
Research

Serologic Screening of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Cats and Dogs during First Coronavirus Disease Wave, the Netherlands

Shan Zhao, Nancy Schuurman, Wentao Li, Chunyan Wang, Lidwien A.M. Smit, Els M. Broens, Jaap A. Wagenaar, Frank J.M. van Kuppeveld, Berend-Jan Bosch, and Herman EgberinkComments to Author 
Author affiliation: Utrecht University, Utrecht, the Netherlands

Main Article

Figure 3

Pairwise correlation analyses of reactivities acquired for serologic analyses of SARS-CoV-2–exposed cohort, the Netherlands. Pearson correlation coefficient was calculated to determine the correlation between the reactivities of RBD ELISA vs. S1 ELISA (A), RBD ELISA vs. VNT (B), S1 ELISA vs. VNT (C), and N ELISA vs. VNT (D). Cat serum samples (n = 44) were indicated in dots and the dog sample (n = 1) in triangle. Dotted lines show the positive cutoff levels. IC50, 50% inhibitory concentration; N, nucleocapsid; OD, optical density; RBD, receptor-binding domain; S1, spike protein subunit 1; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; VNT, virus neutralization titer.

Figure 3. Pairwise correlation analyses of reactivities acquired for serologic analyses of SARS-CoV-2–exposed cohort, the Netherlands. Pearson correlation coefficient was calculated to determine the correlation between the reactivities of RBD ELISA vs. S1 ELISA (A), RBD ELISA vs. VNT (B), S1 ELISA vs. VNT (C), and N ELISA vs. VNT (D). Cat serum samples (n = 44) were indicated in dots and the dog sample (n = 1) in triangle. Dotted lines show the positive cutoff levels. IC50, 50% inhibitory concentration; N, nucleocapsid; OD, optical density; RBD, receptor-binding domain; S1, spike protein subunit 1; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; VNT, virus neutralization titer.

Main Article

Page created: February 21, 2021
Page updated: April 20, 2021
Page reviewed: April 20, 2021
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