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Volume 27, Number 7—July 2021

Trypanosoma cruzi in Nonischemic Cardiomyopathy Patients, Houston, Texas, USA

Melissa S. NolanComments to Author , David Aguilar1, Arunima Misra2, Sarah M. Gunter, Tim Erickson, Rodion Gorchakov3, Hilda Rivera, Susan P. Montgomery, and Kristy O. Murray
Author affiliations: University of South Carolina, Columbia, South Carolina, USA (M.S. Nolan); Baylor College of Medicine, Houston, Texas, USA (M.S. Nolan, D. Aguilar, A. Misra, S.M. Gunter, T. Erickson, R. Gorchakov, K.O. Murray); Harris Health System–Ben Taub Hospital, Houston (A. Misra); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (H. Rivera, S.P. Montgomery)

Main Article


Characteristics of patients enrolled in a cross-sectional study of Trypanosoma cruzi infections in Latinx cardiomyopathy patients at a tertiary care facility† and results of 4 diagnostic assays, Houston, Texas, USA, 2015–2017*

ID Age, y/sex State, country of birth True positive†§ BCM testing
CDC testing
Stat-Pak Hemagen Weiner EIA TESA blot
CM-013 79/F Guerrero, Mexico No Faint positive NP
CM-014 66/M La Union, El Salvador Yes + + + +
CM-017 62/M San Salvador, El Salvador Yes + + + +
CM-037 73/F El Salvador‡ Yes Faint positive + +
CM-048 54/M Texas, USA No Faint Positive NP
CM-058 68/F Michoacan, Mexico No - + NP
CM-082 70/F Tegucigalpa, Honduras Yes + + + +
CM-116 34/M Acapulco, Mexico No Faint positive NP
CM-121 77/M Maracay, Venezuela Yes + + + +
CM-143 42/M San Miguel, El Salvador Yes + + + +
CM-155 73/M Unreported‡ No Faint positive NP
CM-174 78/M Guerrero, Mexico Yes + + + +
CM-197 62/M Tamaulipas, Mexico No + NP
CM-243 54/M Durango, Mexico No Faint positive NP

*All patients were of White race and Latinx ethnicity. A total of 83 patients tested negative by STAT-PAK (Chembio Diagnostic Systems, Inc., and Hemagen (Hemagen Diagnostics, Inc., This table displays the 14 patients who tested positive on >1 of the screener assays, whose samples where then sent to CDC for testing. None of the 83 patients who tested negative by the 2 screening assays had samples sent to CDC for confirmation testing. BCM, Baylor College of Medicine; CDC, Centers for Disease Control and Prevention; EIA, enzyme immunoassay; ID, identification; NP, not performed; –, negative; +, positive. †True positive refers to the CDC guidelines recommending a minimum of >2 positive test results using >2 different diagnostic assay techniques ( ‡Participants choose not to answer state, country of birth, or both because of personal concerns.

Main Article

1Current affiliation: University of Texas Health Science Center, Houston, Texas, USA.

2Current affiliation: Michael E. Debakey Veterans Affairs Medical Center, Houston, Texas, USA.

3Current affiliation: King Abdullah University of Science and Technology, Thuwal, Saudia Arabia.

Page created: May 13, 2021
Page updated: June 17, 2021
Page reviewed: June 17, 2021
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