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Volume 27, Number 7—July 2021
Dispatch

Trypanosoma cruzi in Nonischemic Cardiomyopathy Patients, Houston, Texas, USA

Melissa S. NolanComments to Author , David Aguilar1, Arunima Misra2, Sarah M. Gunter, Tim Erickson, Rodion Gorchakov3, Hilda Rivera, Susan P. Montgomery, and Kristy O. Murray
Author affiliations: University of South Carolina, Columbia, South Carolina, USA (M.S. Nolan); Baylor College of Medicine, Houston, Texas, USA (M.S. Nolan, D. Aguilar, A. Misra, S.M. Gunter, T. Erickson, R. Gorchakov, K.O. Murray); Harris Health System–Ben Taub Hospital, Houston (A. Misra); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (H. Rivera, S.P. Montgomery)

Main Article

Table

Characteristics of patients enrolled in a cross-sectional study of Trypanosoma cruzi infections in Latinx cardiomyopathy patients at a tertiary care facility† and results of 4 diagnostic assays, Houston, Texas, USA, 2015–2017*

ID Age, y/sex State, country of birth True positive†§ BCM testing
 CDC testing
Stat-Pak Hemagen Weiner EIA TESA blot
CM-013 79/F Guerrero, Mexico No Faint positive – – NP
CM-014 66/M La Union, El Salvador Yes + + + +
CM-017 62/M San Salvador, El Salvador Yes + + + +
CM-037 73/F El Salvador‡ Yes Faint positive – + +
CM-048 54/M Texas, USA No Faint Positive – – NP
CM-058 68/F Michoacan, Mexico No - + – NP
CM-082 70/F Tegucigalpa, Honduras Yes + + + +
CM-116 34/M Acapulco, Mexico No Faint positive – – NP
CM-121 77/M Maracay, Venezuela Yes + + + +
CM-143 42/M San Miguel, El Salvador Yes + + + +
CM-155 73/M Unreported‡ No Faint positive – – NP
CM-174 78/M Guerrero, Mexico Yes + + + +
CM-197 62/M Tamaulipas, Mexico No + – – NP
CM-243 54/M Durango, Mexico No Faint positive – – NP

*All patients were of White race and Latinx ethnicity. A total of 83 patients tested negative by STAT-PAK (Chembio Diagnostic Systems, Inc., https://chembio.com) and Hemagen (Hemagen Diagnostics, Inc., https://www.hemagen.com). This table displays the 14 patients who tested positive on >1 of the screener assays, whose samples where then sent to CDC for testing. None of the 83 patients who tested negative by the 2 screening assays had samples sent to CDC for confirmation testing. BCM, Baylor College of Medicine; CDC, Centers for Disease Control and Prevention; EIA, enzyme immunoassay; ID, identification; NP, not performed; –, negative; +, positive. †True positive refers to the CDC guidelines recommending a minimum of >2 positive test results using >2 different diagnostic assay techniques (https://www.cdc.gov/parasites/chagas/healthprofessionals/dx.html). ‡Participants choose not to answer state, country of birth, or both because of personal concerns.

Main Article

1Current affiliation: University of Texas Health Science Center, Houston, Texas, USA.

2Current affiliation: Michael E. Debakey Veterans Affairs Medical Center, Houston, Texas, USA.

3Current affiliation: King Abdullah University of Science and Technology, Thuwal, Saudia Arabia.

Page created: May 13, 2021
Page updated: June 17, 2021
Page reviewed: June 17, 2021
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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