TY - JOUR
AU - Huber, Laura
AU - Agunos, Agnes
AU - Gow, Sheryl
AU - Carson, Carolee
AU - Van Boeckel, Thomas
T1 - Reduction in Antimicrobial Use and Resistance to Salmonella, Campylobacter, and Escherichia coli in Broiler Chickens, Canada, 2013–2019
T2 - Emerging Infectious Disease journal
PY - 2021
VL - 27
IS - 9
SP - 2434
SN - 1080-6059
AB -
Antimicrobial use contributes to the global rise of antimicrobial resistance (AMR). In 2014, the poultry industry in Canada initiated its Antimicrobial Use Reduction Strategy to mitigate AMR in the poultry sector. We monitored trends in antimicrobial use and AMR of foodborne bacteria (Salmonella, Escherichia coli, and Campylobacter) in broiler chickens during 2013 and 2019. We quantified the effect of antimicrobial use and management factors on AMR by using LASSO regression and generalized mixed-effect models. AMR in broiler chickens declined by 6%–38% after the decrease in prophylactic antimicrobial use. However, the withdrawal of individual compounds, such as cephalosporins and fluoroquinolones, prompted an increase in use of and resistance levels for other drug classes, such as aminoglycosides. Canada’s experience with antimicrobial use reduction illustrates the potential for progressive transitions from conventional antimicrobial-dependent broiler production to more sustainable production with respect to antimicrobial use.
KW - foodborne pathogens
KW - antimicrobial resistance
KW - antimicrobial use
KW - food safety
KW - animal production
KW - Salmonella
KW - Campylobacter
KW - Escherichia coli
KW - broiler chickens
KW - bacteria
DO - 10.3201/eid2709.204395
UR - https://wwwnc.cdc.gov/eid/article/27/9/20-4395_article
ER - End of Reference