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Volume 28, Number 1—January 2022

Serotype Replacement after Introduction of 10-Valent and 13-Valent Pneumococcal Conjugate Vaccines in 10 Countries, Europe

Germaine HanquetComments to Author , Pavla Krizova, Tina Dalby, Shamez N. Ladhani, J. Pekka Nuorti, Kostas Danis, Jolita Mereckiene, Mirjam J. Knol, Brita A. Winje, Pilar Ciruela, Sara de Miguel, Maria Eugenia Portillo, Laura MacDonald, Eva Morfeldt, Jana Kozakova, Palle Valentiner-Branth, Norman K. Fry, Hanna Rinta-Kokko, Emmanuelle Varon, Mary Corcoran, Arie van der Ende, Didrik F. Vestrheim, Carmen Munoz-Almagro, Juan-Carlos Sanz, Jesus Castilla, Andrew Smith, Birgitta Henriques-Normark, Edoardo Colzani, Lucia Pastore-Celentano, Camelia Savulescu, and the SpIDnet group1
Author affiliations: Epiconcept, Paris, France (G. Hanquet, C. Savulescu); Antwerp University, Antwerp, Belgium (G. Hanquet); National Institute of Public Health, Prague, Czech Republic (P. Krizova, J. Kozakova); Statens Serum Institut, Copenhagen, Denmark (T. Dalby, P. Valentiner-Branth); Public Health England, London, UK (S.N. Ladhani, N.K. Fry); Tampere University, Tampere, Finland (J.P. Nuorti); Finnish Institute for Health and Welfare, Helsinki, Finland (J.P. Nuorti, H. Rinta-Kokko); Santé Publique France, the National Public Health Agency, Saint-Maurice, France (K. Danis); Health Protection Surveillance Centre, Dublin, Ireland, UK (J. Mereckiene); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (M.J. Knol); Norwegian Institute of Public Health, Oslo, Norway (B.A. Winje, D.F. Vestrheim); Public Health Agency of Catalonia, Barcelona, Spain (P. Ciruela); CIBER Epidemiología y Salud Pública, Madrid, Spain (P. Ciruela, C. Munoz-Almagro, J. Castilla); General Directorate of Public Health–Madrid Region, Madrid (S. de Miguel, J.-C. Sanz); Navarra Hospital Complex–IdiSNA, Pamplona, Spain (M.E. Portillo); Public Health Scotland, Glasgow, Scotland, UK (L. MacDonald); Public Health Agency of Sweden, Stockholm, Sweden (E. Morfeldt); Centre de Recherche Clinique et Biologique, Creteil, France (E. Varon); Children’s Health Ireland (CHI) at Temple Street, Dublin (M. Corcoran); Academic Medical Center, Amsterdam, the Netherlands (A. van der Ende); Hospital Sant Joan de Déu, Barcelona (C. Munoz-Almagro); Universitat Internacional of Catalunya, Barcelona (C. Munoz-Almagro); Public Health Institute of Navarra–IdiSNA, Pamplona (J. Castilla); University of Glasgow, Glasgow, Scotland, UK (A. Smith); Karolinska Institutet, Stockholm (B. Henriques-Normark); K; arolinska University Hospital, Solna, Sweden (B. Henriques-Normark); European Centre for Disease Prevention and Control, Stockholm (E. Colzani, L. Pastore-Celentano)

Main Article

Table 2

Categories of pneumococcal serotypes according to vaccine serotypes*

Category Serotypes included
PCV7 4, 6B, 9V, 14, 18C, 19F, and 23F
PCV10 non-7 (in PCV10 and not PCV7) 1, 5, and 7F
PCV13 non-10 (in PCV13 and not PCV10) 3, 6A, and 19A
Non-PCV10 Any serotype not in PCV10
Non-PCV13 Any serotype not in PCV13
PPV23 non-PCV13 (in PPV23 and not PCV13) 2, 8, 9N, 10A, 11A, 12F, 15B, 17F, 20, 22F, and 33F
Nonvaccine (not in PCV13 or PPV23)
Any serotype not in PCV13 and not in PPV23
New vaccines
PCV15 non-13 (in PCV15 and not PCV13) 22F and 33F
PCV20 non-13 (in PCV20 and not PCV13) 8, 10A, 11A, 12F, 15B, 22F and 33F

*PCV, pneumococcal conjugate vaccine; PCV7, 7-valent pneumococcal conjugate vaccine; PCV10, 10-valent pneumococcal conjugate vaccine; PCV13, 13-valent pneumococcal conjugate vaccine; PPV23, 23-valent pneumococcal polysaccharide vaccine.

Main Article

1Members of the SpIDnet group who contributed are listed at the end of this article.

Page created: November 15, 2021
Page updated: December 20, 2021
Page reviewed: December 20, 2021
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