TY - JOUR AU - Cucco, Lucilla AU - Paniccià, Marta AU - Massacci, Francesca Romana AU - Morelli, Alessandra AU - Ancora, Massimo AU - Mangone, Iolanda AU - Di Pasquale, Adriano AU - Luppi, Andrea AU - Vio, Denis AU - Cammà, Cesare AU - Magistrali, Chiara Francesca T1 - New Sequence Types and Antimicrobial Drug–Resistant Strains of Streptococcus suis in Diseased Pigs, Italy, 2017–2019 T2 - Emerging Infectious Disease journal PY - 2022 VL - 28 IS - 1 SP - 139 SN - 1080-6059 AB - Streptococcus suis is a pathogen associated with severe diseases in pigs and humans. Human infections have a zoonotic origin in pigs. To assess circulating strains, we characterized the serotypes, sequence types, and antimicrobial susceptibility of 78 S. suis isolates from diseased farmed pigs in Italy during 2017–2019. Almost 60% of infections were caused by serotypes 1/2 and 9. All but 1 of the serotype 2 and 1/2 isolates were confined to a single cluster, and serotype 9 isolates were distributed along the phylogenetic tree. Besides sequence type (ST) 1, the serotype 2 cluster included ST7, which caused severe human infections in China in 1998 and 2005. A large proportion of serotype 9 isolates, assigned to ST123, were resistant to penicillin. The emergence of this clone threatens the successful treatment of S. suis infection. Characterizing S. suis isolates from pigs will promote earlier detection of emerging clones. KW - Streptococcus suis KW - infection KW - serotype KW - virulence KW - swine KW - penicillin KW - Italy KW - bacteria KW - streptococci KW - antimicrobial resistance DO - 10.3201/eid2801.210816 UR - https://wwwnc.cdc.gov/eid/article/28/1/21-0816_article ER - End of Reference