Volume 28, Number 1—January 2022
CME ACTIVITY - Synopsis
Fungal Infections Caused by Kazachstania spp., Strasbourg, France, 2007–2020
Charlotte Kaeuffer, Mathieu Baldacini, Tiffany Ruge, Yvon Ruch, Yves-Jean Zhu, Manon De Cian, Guillaume Philouze, Philippe Bachellier, Julie Denis, Nicolas Lefebvre, Francis Schneider, Yves Hansmann, Valérie Letscher-Bru, Raoul Herbrecht, Marcela Sabou, and François Danion
Table 1
Clinical characteristics of Kazachstania spp. infections and colonizations, Strasbourg, France, 2007–2020*
| Patient | Age, y/sex | Underlying condition | Exposure | Type of infection | Therapy | Outcome |
|---|---|---|---|---|---|---|
| 1 | 67/F | Diabetes, endometrial cancer (remission) | Pigeon | Fungemia + UTI | FLC + CAS | Survived |
| 2 | 63/F | Esophagus squamous cell carcinoma | Pigeon | Mediastinitis after gastric ulceration | CAS | Survived |
| 3 | 66/M | CDP (endocrine carcinoma), recurrent angiocholitis | NA | Angiocholitis | FLC, surgery† | Survived |
| 4 | 84/F | Esophageal achalasia | None | Esophagitis | PPI, surgery‡ | Survived |
| 5 | 68/F | CVID, gastro–jejunal anastomotic stenosis | NA | Colonization | None | Survived |
| 6 | 46/M | Caustic esophageal stenosis, pneumonia |
NA | Colonization | None | Survived |
| 7 | 59/F | Systemic scleroderma | NA | Colonization | None | Died (cardiogenic shock) |
| 8 | 40/M | Former smoker, Staphylococcus ventilator-associated pneumonia | NA | Colonization | None | Survived |
| 9 | 51/F | AutoHSCT for oculo-cerebral NHL | NA | Colonization | FLC | Survived |
| 10 | 60/M | Proven Mycobacterium fortuitum infection | NA | Colonization | None | Survived |
| 11 | 59/M | COPD, emphysema, denutrition | NA | Colonization | None | Survived |
| 12 | 77/M | Congestive heart failure, ischemic cardiomyopathy, smoker | NA | Colonization | None | Died; multiorgan failure after cardiac surgery |
| 13 | 66/M | Angioimmunoblastic T-cell lymphoma, neutropenia, pulmonary tuberculosis | NA | Colonization | None | Died 5 mo later; cerebral toxoplasmosis, T-cell lymphoma progression |
*AutoHSCT, autologous hematopoietic stem cell transplantation; CDP, cephalic duodenopancreatectomy; CAS, caspofungin; COPD, chronic obstructive pulmonary disease; CVID, common variable immunodeficiency; FLC, fluconazole; NHL, non-Hodgkin lymphoma; NA, not applicable; PPI, proton pump inhibitor; UTI, urinary tract infection. †Degastrogastrectomy and hepatico–jejunal and gastrointestinal anastomosis. ‡Peroral endoscopic myotomy to treat achalasia.
Page created: November 10, 2021
Page updated: December 17, 2021
Page reviewed: December 17, 2021
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