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Volume 28, Number 10—October 2022
Synopsis

Seasonality of Common Human Coronaviruses, United States, 2014–20211

Melisa M. ShahComments to Author , Amber Winn, Rebecca M. Dahl, Krista L. Kniss, Benjamin J. Silk, and Marie E. Killerby
Author affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Main Article

Table 1

Onset, peak, and offset dates for 4 common HCoVs and percentage detection, by season, from weekly aggregated data submitted to the National Respiratory and Enteric Virus Surveillance System, United States, July 2014–November 2021*

Season (MMWR wk) Date (MMWR wk)
HCoV, %
Onset Peak Offset OC43 NL63 HKU1 229E
2014–15 (31–30) 2014 Nov 1 (44) 2015 Feb 7 (5) 2015 Jun 27 (25) 6.3 23.5 58.8 11.4
2015–16 (31–30) 2015 Nov 7 (44) 2016 Feb 13 (6) 2016 May 14 (19) 31.1 34.8 29.4 4.8
2016–17 (31–30) 2016 Nov 12 (45) 2017 Feb 4 (5) 2017 Apr 29 (17) 1.8 10.0 56.8 31.4
2017–18 (31–30) 2017 Oct 21 (42) 2018 Jan 6 (1) 2018 Apr 21 (16) 33.5 39.3 25.8 1.4
2018–19 (31–30) 2018 Nov 10 (45) 2019 Feb 9 (6) 2019 May 11 (19) 5.8 25.3 49.9 19.0
2019–20 (31–30) 2019 Nov 2 (44) 2020 Jan 18 (3) 2020 Apr 18 (16) 51.9 29.5 14.2 4.3
2020–21 (31–44) 2021 Jan 23 (03) 2021 May 22 (20) Not reached† 1.6 31.6 55.8 10.9

*Dates for season onset, peak, and offset for all seasons are based on the retrospective slope 10 method, which uses a centered 5-week moving average of weekly detections with normalization to peak to define seasonal inflections. Seasons were defined as starting on MMWR week 31 (beginning of August) of each year through MMWR week 30 (end of July) of the following year (https://ndc.services.cdc.gov/wp-content/uploads/MMWR_Week_ overview.pdf). For the last 2020–21 season, data were included from August 2021–November 2022 because of the delayed seasonal start. The percent of positive detections by each HCoV type by season (with the denominator being total positive detections of any HCoV type for that season) is included in the final 4 columns. HCoV, human coronavirus. †By November of 2021, normalized values had not reached the requirement for offset for the 2020–21 season.

Main Article

1Preliminary results from this study were presented at the IDWeek Virtual Conference 2021,

September 29–October 3, 2021.

Page created: August 25, 2022
Page updated: September 20, 2022
Page reviewed: September 20, 2022
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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