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Volume 28, Number 11—November 2022
CME ACTIVITY - Synopsis

Multispecies Outbreak of Nocardia Infections in Heart Transplant Recipients and Association with Climate Conditions, Australia

Jonathan Li, Cindy Lau, Naomi Anderson, Fay Burrows, Feras Mirdad, Lilibeth Carlos, Andrew J. Pitman, Kavitha Muthiah, David R. Darley, David Andresen, Peter Macdonald, Deborah Marriott1, and Nila J. Dharan1Comments to Author 
Author affiliations: St Vincent's Hospital Sydney, Darlinghurst, New South Wales, Australia (J. Li, C. Lau, N. Anderson, F. Burrows, F. Mirdad, L. Carlos, K. Muthiah, D.R. Darley, D. Andresen, P. Macdonald, D. Marriott, N.J. Dharan); Australian Research Council Centre of Excellence for Climate Extremes and Climate Change Research Centre, at UNSW Sydney, Sydney, New South Wales(A.J. Pitman); Victor Chang Cardiac Research Institute, Darlinghurst (K. Muthiah, P. Macdonald); UNSW Sydney, Sydney (D.R. Darley, N.J. Dharan); University of Notre Dame, Sydney (D. Andresen)

Main Article

Table 4

Climate conditions and Nocardia incidence before, during, and after a Nocardia outbreak among heart and lung transplant recipients, Greater Sydney, New South Wales, Australia, January 2018–December 2019*

Characteristic Preoutbreak, Jun 2015–Dec 2017 Outbreak,
Jan 2018–Dec 2019		 Postoutbreak
Jan 2020–Mar 2021		 p value
Nocardia cases/mo 0.16 0.46 0.07
Average monthly precipitation, mm/mo 60.4 40.0 103.2 <0.01
Average monthly temperature °C 17.0 17.8 17.8 0.79
Average monthly dryness* 0.4 0.3 0.5 <0.01
Average monthly windspeed, m/s 1.0 0.9 1.0 0.62
Average monthly erodibility† 0.1 0.2 0.1 0.26

*Ratio of evaporation to potential evaporation, such that 0.0 is perfectly dry and 1.0 is perfectly wet. †Calculated by the formula (1 – dryness) × windspeed.

Main Article

1These authors contributed equally to this article.

Page created: September 20, 2022
Page updated: October 21, 2022
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