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Volume 28, Number 12—December 2022
CME ACTIVITY - Research

Acinetobacter baumannii among Patients Receiving Glucocorticoid Aerosol Therapy during Invasive Mechanical Ventilation, China

Wenchao Zhang1, Mei Yin1, Wei Li, Nana Xu, Haining Lu, Weidong Qin, Hui Han, Chen Li, Dawei Wu, and Hao WangComments to Author 
Author affiliations: Qilu Hospital of Shandong University, Jinan, China (W. Zhang, M. Yin, W. Li, N. Xu, W. Qin, H. Han, C. Li, H. Wang); Qingdao Branch, Qilu Hospital of Shandong University, Qingdao, China (H. Lu, D. Wu)

Main Article

Table 2

Multivariate analysis of risk factors for Acinetobacter baumannii among patients during invasive mechanical ventilation, China*

Variables p value Hazard ratio (95% CI)
Underlying conditions
Cardiovascular diseases 0.054 1.394 (0.994–1.955)
Chronic renal insufficiency 0.730 0.937 (0.648–1.356)
COPD and asthma 0.132 1.299 (0.924–1.825)
Type 2 diabetes mellitus 0.325 1.197 (0.837–1.714)
Current or former smoker
 0.098
 1.307 (0.951–1.797)
Treatment
  No aerosol inhalation Referent
  Glucocorticoid aerosol inhalation 0.038 1.528 (1.024–2.278)
  Aerosol inhalation without glucocorticoid 0.524 0.829 (0.467–1.475)
Broad-spectrum antimicrobial drugs, >7 d 0.001 7.238 (2.758–15.788)
Invasive mechanical ventilation, >5 d 0.001 2.381 (1.664–3.405)
Vasopressor treatment, >3 d <0.001 2.060 (1.402–3.028)
Renal dialysis, >3 d
 0.841
 1.046 (0.675–1.620)
APACHE II score 0.586 0.992 (0.965–1.020)

*Results are from model 2; only variables with p<0.1 in univariate analysis were included. APACHE II, Acute Physiology and Chronic Health Evaluation II; COPD, chronic obstructive pulmonary disease.

Main Article

1These authors contributed equally to this article.

Page created: October 17, 2022
Page updated: November 17, 2022
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